Author

A. Sickmann

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1 Immunology· 1 Microbiology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:protein folding & dynamics· 2 Assay:proteomics· 2 Organism:Arabidopsis· 1 Assay:bulk RNA-seq· 1

Frequent Co-Authors

M. Gunzer· 2 shared A. A. Tuz· 1 shared A. Beer· 1 shared A. Covallero· 1 shared A. Goedecke· 1 shared A. Grueneboom· 1 shared A. Hasenberg· 1 shared A. I. Casas· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersImmunology

M. Gunzer

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Peyers Patch B cells undergo cell death via neutrophil-released toxic DNA following sterile tissue injury

A. A. Tuz, A. Beer, M. Gallert, D. Ttoouli, S. Ghosh, S. P. Sata, A. Kraus, F. Zwirnlein, V. Kaygusuz, V. Lakovic, A. Qefalia, M. Antler, S. Korste, B. Kaltwasser, H. Abdelrahman, , V. Singh

The paper shows that sterile tissue injury causes B cell death in Peyers patches via neutrophil-released toxic DNA, leading to tissue shrinkage and reduced secretory IgA.

bioRxiv · Nov 9, 2022Immunology

LUBAC assembles a signaling platform at mitochondria for signal amplification and shuttling of NF-ĸB to the nucleus

Z. Wu, L. A. Berlemann, V. Bader, D. A. Sehr, E. Eilers, A. Covallero, J. Meschede, L. Angersbach, C. Showkat, J. B. Michaelis, C. Muench, B. Rieger, D. Namgaladze, M. G. Herrera, F. C. Fiesel, , K. F. Winklhofer

This study shows that LUBAC assembles at mitochondria to amplify and shuttle NF-κB signals to the nucleus during TNF activation.

bioRxiv · May 27, 2022 · PreprintCell Biology

Universally available herbal teas based on sage and perilla elicit potent antiviral activity against SARS-CoV-2 variants of concern by HMOX-1 upregulation in human cells

V. T. K. Le-Trilling, D. Mennerich, C. Schuler, R. Sakson, J. K. Lill, D. Kopczynski, S. Loroch, Y. Flores-Martinez, B. Katschinski, K. Wohlgemuth, M. Gunzer, F. Meyer, U. Dittmer, A. Sickmann, M. Trilling

bioRxiv · Nov 18, 2020Microbiology

Coordination and assembly of protein complexes encoded across mitochondrial and nuclear genomes is assisted by CLPP2 in Arabidopsis thaliana

J. Petereit, O. Duncan, M. Murcha, R. Fenske, E. Cincu, J. Cahn, A. Pruzinska, L. Kollipara, S. Wortekamp, A. Sickmann, J. Lee, R. Lister, H. Millar, S. HUANG

The paper shows that CLPP2 in Arabidopsis thaliana aids in coordinating and assembling protein complexes encoded by both mitochondrial and nuclear genomes, affecting mitochondrial protein homeostasis.

bioRxiv · Jan 22, 2020Plant Biology

Nitrative signaling into cardiac lactate dehydrogenase Trp324 modulates active site loop mobility and activity under metabolic stress

C. Nogales, J. Frihoff, D. Thoenges, R. B. Sessions, A. Sickmann, T. Nedvetskaya, C. Ibarra-Alvarado, V. Schmitz, P. Rosen, A. Goedecke, A. Jovanovic, D. H. Perlman, A. Klinke, S. Baldus, A. I. Casas, , H. H. H. W. Schmidt

This study identifies Trp324 nitration in lactate dehydrogenase as a physiological signaling mechanism modulating enzyme activity under metabolic stress.

bioRxiv · Jan 15, 2019 · PreprintBiochemistry