M. Roger

Subclinical Atherosclerosis is Associated with Discrepancies in BAFF and APRIL Levels and Altered Breg Potential of Precursor-like Marginal Zone B-Cells in HIV Treated Individuals

The paper investigates the association between BAFF and APRIL levels and subclinical atherosclerosis in HIV-treated individuals, finding elevated BAFF correlates with CVD risk factors while APRIL shows inverse correlations.

Excess BAFF Alters NR4As Expression Levels and Breg Function of Human Precursor-like Marginal Zone B-cells in the Context of HIV-1 infection

This study shows that excess BAFF reduces Breg function and NR4A expression in MZp B-cells from HIV-infected individuals, which may impair immune surveillance.

Three-dimensional structure of the single domain cupredoxin AcoP

This paper determines the 3D structure of AcoP, a cupredoxin from Acidithiobacillus ferrooxidans, revealing unique structural features and copper coordination that explain its redox properties and function.

An anti-SARS-CoV-2 non-neutralizing antibody with Fc-effector function defines a new NTD epitope and delays neuroinvasion and death in K18-hACE2 mice

Contribution of single mutations to selected SARS-CoV-2 emerging variants Spike antigenicity

The paper evaluates how single mutations in SARS-CoV-2 Spike protein affect antigenicity and ACE2 binding in emerging variants.

Impact of temperature on the affinity of SARS-CoV-2 Spike for ACE2

This study investigates how temperature affects SARS-CoV-2 Spike protein affinity for ACE2, finding increased binding at low temperatures, which is mitigated by the N501Y mutation.

A single BNT162b2 mRNA dose elicits antibodies with Fc-mediated effector functions and boost pre-existing humoral and T cell responses

This study shows a single dose of the BNT162b2 mRNA vaccine elicits strong antibody and T cell responses, including Fc-mediated effector functions, and boosts pre-existing immunity in previously infected individuals.

Harnessing Escherichia coli for bio-based production of formate under pressurized H2 and CO2 gases.

This study engineers E. coli to produce formate from H2 and CO2 under pressurized conditions, showing growth deficiency at high H2:CO2 pressures.

Cross-sectional evaluation of humoral responses against SARS-CoV-2 Spike

This study evaluates humoral responses against SARS-CoV-2 Spike in 106 infected individuals, finding persistent RBD-specific IgG and declining neutralizing activity over time.

TIGIT is upregulated by HIV-1 infection and marks a highly functional adaptive and mature subset of natural killer cells

This study shows that TIGIT is upregulated on NK cells in untreated HIV+ individuals and marks a functional, mature NK cell subset with enhanced responses to HIV-infected targets.

Efficient hydrogen-dependent carbon dioxide reduction by Escherichia coli

This paper demonstrates that Escherichia coli's formate hydrogenlyase complex can efficiently reduce carbon dioxide to formate under controlled pressure conditions.