B. Goldstein

Long-distance Wnt transport in axons highlights cell type-specific modes of Wnt transport in vivo

The paper investigates long-distance Wnt transport in C. elegans axons, revealing a novel mode of transport and cell type-specific mechanisms.

Architecture of the cortical actomyosin network driving apical constriction in C. elegans

The paper shows that the actomyosin network driving apical constriction in C. elegans gastrulation lacks the sarcomere-like architecture seen in Drosophila, indicating diverse mechanisms for this process.

Tardigrade small heat shock proteins can limit desiccation-induced protein aggregation

This study identifies and characterizes small heat shock proteins in tardigrades that improve desiccation tolerance by limiting protein aggregation.

The C. elegans Anchor Cell Transcriptome: Ribosome Biogenesis Drives Cell Invasion through Basement Membrane

The paper identifies ribosome biogenesis and endomembrane expansion as key drivers of C. elegans anchor cell invasion through basement membrane using transcriptomic and functional analyses.

Deconstructing olfactory epithelium developmental pathways in esthesioneuroblastoma

This study uses bulk and single-cell RNA-sequencing to analyze ENB tumor samples and identifies cell-type changes and prognostic markers associated with tumor grade.

Molecular aspects of multivalent engagement between Syk and FcϵRIγ

The paper models and experimentally validates that cis binding of Syk to FcεRIγ is more effective for signaling than trans binding, with Y130 phosphorylation reducing cis binding.

Predicting division planes of three-dimensional cells by soap-film minimization

The paper develops a mathematical model to predict cell division planes in plants and animals by simulating soap-film minima, showing it matches observed division sites and avoids unfavorable junctions.

Optogenetic dissection of mitotic spindle positioning in vivo

This study uses optogenetics to dissect mitotic spindle positioning in C. elegans embryos, showing that G-GTP signaling is dispensable and LIN-5Mud/NuMA activates dynein-dependent forces.

LITE microscopy: a technique for high numerical aperture, low photobleaching fluorescence imaging

The paper introduces LITE microscopy, a technique that improves resolution and brightness while reducing photodamage in fluorescence imaging.