Author

B. Pierce

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Biochemistry· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:proteomics· 2 Approach:deep learning· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Amcheslavsky· 1 shared A. C. Kruse· 1 shared A. K. Andrianov· 1 shared A. Marin· 1 shared A. Wallace· 1 shared C. McMahon· 1 shared D. Dey· 1 shared E. A. Toth· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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1 shared paperMicrobiology

A. Amcheslavsky

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Diverse mutant selection windows shape spatialheterogeneity in evolving populations

E. S. King, B. Pierce, M. Hinczewski, J. G. Scott

This paper introduces fitness seascapes to model genotype-by-environment interactions, enabling more accurate prediction of drug resistance evolution by analyzing spatially heterogeneous mutant selection windows.

bioRxiv · Mar 9, 2023Evolutionary Biology

An Extended Motif in the SARS-CoV-2 Spike Modulates Binding and Release of Host Coatomer in Retrograde Trafficking

D. Dey, S. Singh, S. Khan, M. Martin, N. Schnicker, L. Gakhar, B. Pierce, S. S. Hasan

The paper identifies an extended COPI binding motif in the SARS-CoV-2 spike protein that modulates its interaction with COPI subunits and is critical for retrograde trafficking.

bioRxiv · Sep 3, 2021Biochemistry

Oral administration of a single anti-CfaE nanobody provides broadly cross-protective immunity against major pathogenic Enterotoxigenic Escherichia coli strains

A. Amcheslavsky, A. Wallace, M. Ejemel, Q. Li, C. McMahon, M. Stoppato, S. Giuntini, Z. A. Schiller, J. Pondish, J. R. Toomey, R. Schneider, J. Meisinger, R. Heukers, A. C. Kruse, E. M. Barry, , Y. Wang

This study shows that oral administration of a single nanobody provides broad protection against multiple ETEC strains by targeting conserved epitopes.

bioRxiv · Jun 16, 2020 · PreprintMicrobiology

Structure-based design of hepatitis C virus E2 glycoprotein improves serum binding and cross-neutralization

B. Pierce, Z.-y. Keck, R. Wang, P. Lau, K. J. Garagusi, K. Elkholy, E. A. Toth, R. A. Urbanowicz, J. D. Guest, P. Agnihotri, M. C. Kerzic, A. Marin, A. K. Andrianov, J. K. Ball, R. Mariuzza, , S. Foung

The paper designs optimized HCV E2 glycoproteins to enhance binding and cross-neutralization by modifying antigenic sites and testing immunogenicity in mice.

bioRxiv · Apr 15, 2020Microbiology