Author

C. Chien

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:metabolomics· 1

Frequent Co-Authors

A. B. Molofsky· 1 shared A. Bhattacharyya· 1 shared A. Ghosh· 1 shared A. N. Mogol· 1 shared A. R. Abate· 1 shared A. S. Casiano· 1 shared A. S. Raghavendra· 1 shared A. Wagner· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperImmunology

A. B. Molofsky

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Myeloid-mesenchymal crosstalk drives Arg1-dependent profibrotic metabolism via ornithine in lung fibrosis

P. Yadav, J. Gomez Ortega, P. Dabral, W. Tamaki, C. Chien, K.-C. Chang, N. Biswas, S. Pan, J. Nilsson, X. Yin, A. Bhattacharyya, K. Boostanpour, T. Jujaray, J. Wang, T. Tsukui, , M. Bhattacharya

The paper identifies a myeloid-mesenchymal crosstalk pathway involving Arg1 and ornithine that drives profibrotic metabolism in lung fibrosis.

bioRxiv · Sep 6, 2023Immunology

Targeting metabolic adaptations in the breast cancer liver metastatic niche using dietary approaches to improve endocrine therapy efficacy

Q. Zuo, A. N. Mogol, Y.-J. Liu, A. S. Casiano, C. Chien, J. Drnevich, O. B. Imir, E. Kulkoyluoglu-Cotul, N. H. Park, D. J. Shapiro, B. H. Park, Y. Ziegler, B. S. Katzenellenbogen, E. Aranda, J. D. O'Neill, , Z. Madak-Erdogan

This study identifies a mechanism of endocrine resistance in liver metastases of ER+ breast cancer and shows that a fasting-mimicking diet enhances the efficacy of fulvestrant treatment.

bioRxiv · Sep 7, 2021Cancer Biology