Respiratory mucosal vaccination of peptide-poloxamine-DNA nanoparticles provides complete protection against lethal SARS-CoV-2 challenge
S. Sun, E. Li, G. Zhao, J. Tang, Q. Zuo, L. Cai, C. Xu, C. Sui, Y. Ou, C. Liu, H. Li, Y. Ding, C. Li, D. Lu, W. Zhang, , S. Guan
This study shows that peptide-poloxamine-DNA nanoparticles provide complete protection against lethal SARS-CoV-2 challenge through robust mucosal immunity.
bioRxiv · May 29, 2022Immunology