Author

N. Shroyer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:development & morphogenesis· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

E. Sahin· 2 shared J. Butkus· 2 shared M.-S. Chen· 2 shared S. Patel· 2 shared Y.-H. Lo· 2 shared A. Catic· 1 shared A. Engevik· 1 shared A. Groves· 1 shared

Activity by Year

2018-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersCell Biology

E. Sahin

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Loss of ZNRF3/RNF43 Unleashes EGFR in Cancer

F. Yue, A. T. Ku, P. Stevens, M. Michalski, W. Jiang, J. Tu, Z. Shi, Y. Dou, Y. Wang, X.-H. Feng, G. Hostetter, X. Wu, S. Huang, N. Shroyer, B. Zhang, , Y. Li

The paper shows that ZNRF3/RNF43 ubiquitinates and degrades EGFR, and their loss increases EGFR signaling, promoting cancer growth.

bioRxiv · Jan 10, 2024Cancer Biology

Telomere dysfunction impairs intestinal differentiation andpredisposes to diet-induced colitis

M. Engevik, L. Guo, W.-S. Song, C. Chronowski, V. Akhanov, N. Bosquez, A. Engevik, N. Oezguen, C. Coarfa, N. Putluri, A. Catic, J. Baur, M. Finegold, N. Shroyer, J. Gu, , E. Sahin

This study shows that telomere shortening impairs intestinal differentiation, leading to barrier defects and diet-induced colitis through microbiome modulation and nutrient flux.

bioRxiv · Jul 14, 2022 · PreprintCell Biology

Gfi1-expressing Paneth cells revert to stem cells following intestinal injury

M.-S. Chen, Y.-H. Lo, J. Butkus, W. Zou, Y.-J. Tseng, H.-I. Jen, S. Patel, A. Groves, M. Estes, E. Sahin, M. Frey, P. Dempsey, N. Shroyer

This study shows that Gfi1-expressing secretory cells can revert to stem cells after intestinal injury, with PI3kinase/AKT and WNT signaling enhancing this process.

bioRxiv · Jul 16, 2018 · PreprintCell Biology

Growth Factor Independent 1 is a tumor suppressor gene in colorectal cancer

M.-S. Chen, Y.-H. Lo, X. Chen, C. Williams, J. Donnelly, Z. Criss, S. Patel, J. Butkus, N. Shroyer

This study shows GFI1 acts as a tumor suppressor in colorectal cancer by reducing its expression in advanced stages and inhibiting tumor growth in models.

bioRxiv · Jul 16, 2018Cancer Biology