C. Min

Molecular tension authenticates apoptotic cells being phagocytosed

The paper identifies molecular tension between phosphatidylserine and its receptors as a signal determining phagocytosis of apoptotic cells.

Single-cell morphology encodes functional subtypes of senescence in aging human dermal fibroblasts

This study identifies functional senescence subtypes in aging human dermal fibroblasts using single-cell morphology and machine learning, showing subtype-specific responses to senotherapies.

Construction of Animal Models Based on Exploring Pathological Features and Mechanisms of Different Locations in the Progression of DVT-APTE-CTEPD/CTEPH

This study constructs animal models to simulate different stages of DVT-APTE-CTEPD/CTEPH progression and compares their effectiveness in capturing pathological features.

AI-driven Classification of Cancer-Associated Fibroblasts Using Morphodynamic and Motile Features

This paper introduces an AI framework to classify cancer-associated fibroblasts using morphodynamic and motile features from live-cell imaging, complementing biomolecular approaches.

Profiling Dynamic Patterns of Single-cell Motility

This study introduces CaMI, a framework to classify single-cell motility patterns, revealing heterogeneity and dynamics not captured by traditional ensemble methods.

Potent SARS-CoV-2 neutralizing antibodies selected from a human antibody library constructed decades ago

The paper identifies potent SARS-CoV-2 neutralizing antibodies from a pre-pandemic human antibody library, showing high somatic hypermutation and specific binding to the spike protein.

SEMA3F-deficient colorectal cancer cells promote lymphangiogenesis: fatty acid metabolism replace glycolysis for energy supply during lymphatic endothelial cells proliferation in tumor hypoxia microenvironment

This study shows SEMA3F-deficient colorectal cancer cells enhance lymphangiogenesis under hypoxia by promoting fatty acid metabolism in lymphatic endothelial cells through IL-6 and PGC-1α-PPAR pathways.

Disease-associated mutations hyperactivate KIF1A motility and anterograde axonal transport of synaptic vesicle precursors

This study shows that disease-associated KIF1A mutations hyperactivate motor activity, leading to increased anterograde axonal transport of synaptic vesicle precursors and contributing to motor neuron disease.