Author

D. Sheng

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 3 Ecology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Assay:cryo-EM· 2 Research Focus:protein structure prediction· 2 Research Focus:ecology & biodiversity· 1 Assay:imaging· 1 Organism:multiple species· 1 Research Focus:protein folding & dynamics· 1 Assay:structural biology· 1

Frequent Co-Authors

M. Hattori· 3 shared J. Wang· 2 shared X. Teng· 2 shared Y. Yu· 2 shared B. Zhang· 1 shared C. Shen· 1 shared C. Yue· 1 shared C.-R. Guo· 1 shared

Activity by Year

2021-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersBiophysics

M. Hattori

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Structural insights into the orthosteric inhibition of P2X receptors by non-ATP-analog antagonists

D. Sheng, C. Yue, F. Jin, Y. Wang, M. Ichikawa, Y. Yu, C.-R. Guo, M. Hattori

The paper determines cryo-EM structures of P2X7 receptor with antagonists and identifies key residues for subtype specificity, aiding in antagonist design.

bioRxiv · Sep 15, 2023Biophysics

Eyes on nature: Embedded vision cameras for multidisciplinary biodiversity monitoring

K. F. A. Darras, M. Balle, W. Xu, Y. Yan, V. G. Zakka, M. Toledo-Hernandez, D. Sheng, W. Lin, B. Zhang, Z. Lan, L. Fupeng, T. C. Wanger

The paper introduces a portable, low-power embedded vision camera system for biodiversity monitoring, demonstrating its application across multiple ecological disciplines with classification accuracies between 55% and 96%.

bioRxiv · Jul 26, 2023 · PreprintEcology

Structural insights into the allosteric inhibition of P2X4 receptors

C. Shen, W. Cui, Y. Zhang, Y. Zhao, D. Sheng, X. Teng, J. Wang, M. Hattori

This study reports cryo-EM structures of zebrafish P2X4 receptors bound to antagonists, revealing ligand-dependent structural changes that explain subtype-specific allosteric inhibition.

bioRxiv · Mar 7, 2023Biophysics

Structural insights into the ion selectivity of the MgtE channel for Mg2+ over Ca2+

X. Teng, D. Sheng, J. Wang, Y. Yu, M. Hattori

The paper determines the high-resolution structure of MgtE TM domain with Ca2+ and shows Mg2+ binds 500-fold stronger than Ca2+.

bioRxiv · Dec 29, 2021Biophysics