Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
7 papers
Recent·Most cited
A. Dumigan, O. Cappa, B. Morris, J. sa-Pessoa Graca Santos, R. Calderon-Gonzalez, G. Mills, R. Lancaster, D. Simpson, A. Kissenpfennig, J. A. Bengoechea
This study identifies a novel host-pathogen interaction where Klebsiella pneumoniae rewires lung macrophages to promote infection by inducing an M(Kp) polarization state.
bioRxiv · Oct 18, 2021 · PreprintMicrobiology
C. G. G. Bamford, L. Broadbent, E. Aranday Cortes, M. McCabe, J. McKenna, D. Courtney, O. Touzelet, A. Ali, G. Roberts, G. Lopez Campos, D. Simpson, C. McCaughey, D. Fairley, K. Mills, U. F. Power, The Breathing Together Consortium
This study investigates how viral and host factors influence SARS-CoV-2 evolution in vitro, identifying genetic changes and their impact on viral fitness in different cell types.
bioRxiv · Jul 16, 2021 · PreprintMicrobiology
T. Huokko, T. Ni, G. Dykes, D. Simpson, P. Brownridge, F. Conradi, R. Beynon, P. Nixon, C. Mullineaux, P. Zhang, L.-N. Liu
The paper investigates thylakoid membrane biogenesis in cyanobacteria by modulating light intensity, revealing the spatial-temporal dynamics of protein complex insertion and membrane organization.
bioRxiv · May 5, 2021Plant Biology
S. Vijayaraj, R. Feltham, M. Rashidi, D. Frank, Z. Liu, D. Simpson, G. Ebert, A. Vince, M. J. Herold, A. J. Kueh, J. Pearson, L. Dagley, J. M. Murphy, A. I. Webb, K. E. Lawlor, J. E. Vince
This study shows that IL-1β is ubiquitylated and degraded to limit its inflammatory activity, with specific ubiquitin modifications and electrostatic interactions playing key roles.
bioRxiv · Mar 15, 2021 · PreprintImmunology
D. Simpson, H. Choi, D. Wang, M. Prescott, A. A. Pitsillides, J. Dudhia, P. D. Clegg, P. Ping, C. T. Thorpe
The paper measures protein turnover rates in collagen and glycoprotein phases of rat Achilles tendon using isotope labeling and mass spectrometry, finding significant differences in proteome dynamics between the two ECM phases.
bioRxiv · Jan 27, 2020Biochemistry
N. J. Haley, K. Merrett, A. J. Buros Stein, D. Simpson, A. Carlson, G. Mitchell, A. Staskevicius, T. Nichols, A. Lehmkuhl, B. Thomsen
The paper assesses CWD susceptibility and progression in farmed whitetail deer with rare PRNP alleles by analyzing infection status and disease stage in over 2100 deer.
bioRxiv · Oct 14, 2019Microbiology