Author

D. Tomar

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 3 Biophysics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cell type annotation· 4 Organism:human· 3 Assay:imaging· 3 Organism:mouse· 3 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

A. Kinder· 3 shared A. Kirabo· 3 shared E. Scudese· 3 shared H. Le· 3 shared M. A. Phillips· 3 shared P. Jadiya· 3 shared P. Katti· 3 shared Z. Vue· 3 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersPhysiology

A. Kinder

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Age-related MICOS Complex Dysregulation Impairs Mitochondrial 3D Architecture and Metabolic Homeostasis in the Liver

S. K. Masenga, A. C. Murphy, P. Venkhatesh, Z. Vue, A. A. Kadam, A. G. Marshall, B. I. Rodriguez, E. Scudese, B. C. Jenkins, A. Crabtree, P. Prasad, E. G. Lopez, H. Le, K. Actkins, E. Zaganjor, , C. P. H Perez

This study investigates age-related changes in mitochondrial structure and function in the liver, identifying MICOS complex dysregulation as a contributor to metabolic and structural impairments.

bioRxiv · Jun 20, 2024 · PreprintPhysiology

The MICOS Complex Regulates Mitochondrial Structure and Oxidative Stress During Age-Dependent Structural Deficits in the Kidney

P. Katti, P. Prasad, S. K. Masenga, P. Venkhatesh, Z. Vue, A. G. Marshall, B. Rodrageaz, H. Le, E. Garza-Lopez, A. Murphy, B. Jenkins, A. Kadam, J. Shao, A. Crabtree, P. Martin, , McReyn

This study investigates age-related mitochondrial structural deficits in the kidney, finding that the MICOS complex is impaired, leading to increased oxidative stress and mitochondrial dysfunction.

bioRxiv · Jun 9, 2024Physiology

3D Mitochondrial Structure in Aging Human Skeletal Muscle: Insights into MFN-2 Mediated Changes

E. Scudese, Z. Vue, P. Katti, A. Marshall, M. Demirci, L. Vang, E. Garza Lopez, K. Neikirk, H. Le, D. Stephens, D. D. Hall, R. Rostami, T. Rodman, K. Kabugi, J.-q. Shao, , A. Hinton

This study investigates age-related changes in mitochondrial 3D structure in human skeletal muscle and shows that exercise can restore mitochondrial integrity through mitofusin 2.

bioRxiv · Nov 13, 2023Biophysics

TMEM65 regulates NCLX-dependent mitochondrial calcium efflux

J. F. Garbincius, O. Salik, H. M. Cohen, C. Choya-Foces, A. S. Mangold, A. D. Makhoul, A. E. Schmidt, D. Y. Khalil, J. J. Doolittle, A. S. Wilkinson, E. K. Murray, M. P. Lazaropoulos, A. N. Hildebrand, D. Tomar, J. W. Elrod

This study identifies TMEM65 as a regulator of NCLX-dependent mitochondrial calcium efflux, showing its role in preventing calcium overload and cell death in excitable tissues.

bioRxiv · Oct 6, 2023Physiology

MICU1 regulates mitochondrial cristae structure and function independent of the mitochondrial calcium uniporter channel

D. Tomar, M. Thomas, J. F. Garbincius, D. W. Kolmetzky, O. Salik, P. Jadiya, A. C. Carpenter, J. W. Elrod

This paper identifies mtCU-independent functions of MICU1, showing it regulates mitochondrial cristae structure and function through interactions with MICOS components.

bioRxiv · Oct 12, 2019Cell Biology