Author

S. Leventhal

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Microbiology· 3 Paleontology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 7 Research Focus:host-pathogen & immune response· 7 Organism:mouse· 4 Organism:non-human primate· 3 Research Focus:drug response / drug discovery· 2 Organism:rat· 2 Research Focus:benchmarking· 1 Approach:statistical model· 1

Frequent Co-Authors

H. Feldmann· 7 shared D. W. Hawman· 5 shared K. Meade-White· 5 shared D. H. Fuller· 4 shared J. Archer· 4 shared S. Randall· 4 shared A. P. Khandhar· 3 shared K. Rosenke· 3 shared

Activity by Year

2020-2024 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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7 shared papersImmunology

H. Feldmann

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

Origin of division of labor is decoupled from polymorphism in colonial animals

S. Leventhal, S. M. Edie, C. Simpson, R. Morrison

The paper shows that polymorphism in cheilostome bryozoans evolved through loss of functions rather than gain, suggesting polymorphism can arise through drift, not division of labor.

bioRxiv · Jul 5, 2024Paleontology

A replicon RNA vaccine induces durable protective immunity from SARS-CoV-2 in nonhuman primates after neutralizing antibodies have waned

M. A. O'Connor, D. W. Hawman, K. Meade-White, S. Leventhal, W. Song, S. Randall, J. Archer, T. B. Lewis, B. Brown, N. Iwayama, C. Ahrens, W. Garrison, S. Wangari, K. A. Guerriero, P. Hanley, , J. H. Erasmus

This study shows a replicon RNA vaccine provides durable protection against SARS-CoV-2 in nonhuman primates even after neutralizing antibodies decline.

bioRxiv · Aug 8, 2022 · PreprintImmunology

Replicating RNA platform enables rapid response to the SARS-CoV-2 Omicron variant and elicits enhanced protection in naïve hamsters compared to ancestral vaccine

D. W. Hawman, K. Meade-White, C. Clancy, J. Archer, T. Hinkley, S. Leventhal, D. Rao, A. Stamper, M. Lewis, R. Rosenke, K. Krieger, S. Randall, A. P. Khandhar, L. Hao, T.-Y. Hsiang, , J. Erasmus

bioRxiv · Jan 31, 2022Microbiology

SARS-CoV2 variant-specific replicating RNA vaccines protect from disease and pathology and reduce viral shedding following challenge with heterologous SARS-CoV2 variants of concern

D. W. Hawman, K. Meade-White, J. Archer, S. Leventhal, D. Wilson, C. Shaia, S. Randall, A. P. Khandhar, T.-Y. Hsiang, M. Gale, P. Berglund, D. H. Fuller, H. Feldmann, J. Erasmus

This study evaluates a replicating RNA vaccine against SARS-CoV-2 variants, showing protection from disease and reduced viral shedding after heterologous challenge.

bioRxiv · Dec 10, 2021Microbiology

Immunocompetent Mouse Model for Crimean-Congo Hemorrhagic Fever Virus

D. W. Hawman, K. Meade-White, S. Leventhal, F. Feldmann, A. Okumura, B. Smith, D. Scott, H. Feldmann

This paper develops an immunocompetent mouse model for CCHFV that replicates human disease severity, enabling better study of host-viral interactions.

bioRxiv · Nov 5, 2020Immunology

Inhibition of SARS-CoV-2 in Vero cell cultures by peptide-conjugated morpholino-oligomers.

K. Rosenke, S. Leventhal, H. Moulton, S. Hatlevig, D. Hawman, H. Feldmann, D. A. Stein

This study evaluates peptide-conjugated morpholino oligomers (PPMO) against SARS-CoV-2 in Vero cells, showing significant viral titer reduction without toxicity.

bioRxiv · Sep 29, 2020Microbiology

Hydroxychloroquine Proves Ineffective in Hamsters and Macaques Infected with SARS-CoV-2

K. Rosenke, M. Jarvis, F. Feldmann, B. Schwarz, A. Okumura, J. Lovaglio, G. Saturday, P. Hanley, K. Meade-White, B. Williamson, F. Hansen, L. Perez-Perez, S. Leventhal, T.-L. Tang-Huau, M. Nason, , H. Feldmann

This study shows hydroxychloroquine does not reduce SARS-CoV-2 replication or improve clinical outcomes in hamsters or macaques.

bioRxiv · Jun 10, 2020 · PreprintPharmacology & Toxicology

Single-dose replicating RNA vaccine induces neutralizing antibodies against SARS-CoV-2 in nonhuman primates

J. H. Erasmus, A. P. Khandhar, A. C. Walls, E. A. Hemann, M. A. O'Connor, P. Murapa, J. Archer, S. Leventhal, J. Fuller, T. Lewis, K. E. Draves, S. Randall, K. A. Guerriero, M. S. Duthie, D. Carter, , D. H. Fuller

bioRxiv · May 28, 2020 · PreprintImmunology