Author

P. Evans

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Microbiology· 2 Cancer Biology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Assay:bulk RNA-seq· 3 Research Focus:cell signaling & trafficking· 3 Research Focus:cell type annotation· 3 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 3 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:development & morphogenesis· 2

Frequent Co-Authors

C. Souilhol· 3 shared V. Ridger· 3 shared H. Roddie· 2 shared J. Serbanovic-Canic· 2 shared L. Canham· 2 shared M. Ariaans· 2 shared M. FRAGIADAKI· 2 shared S. Francis· 2 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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3 shared papersCell Biology

C. Souilhol

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Polymer biodegradation by Halanaerobium promotes reservoir souring during hydraulic fracturing.

G. Scheffer, A. Chakraborty, K. Amundson, R. Khan, M. Wilkins, K. Wrighton, P. Evans, C. R. Hubert

The paper investigates how Halanaerobium metabolizes guar gum in produced water from hydraulic fracturing, showing that polymer biodegradation at 30°C generates fermentation intermediates that contribute to reservoir souring when introduced into subsurface environments at 60°C.

bioRxiv · Jun 16, 2023 · PreprintMicrobiology

Epigenetic regulator genes direct lineage switching in MLL-AF4 leukaemia

R. Tirtakusuma, K. Szoltysek, P. Milne, V. V. Grinev, A. Ptasinska, C. Meyer, S. Nakjang, J. Y. Hehir-Kwa, D. Williamson, P. Cauchy, S. A. Assi, M. R. Imperato, F. Vogiatzi, S. Lin, M. Wunderlich, , M. J Thirman

This study shows that lineage switching in MLL-AF4 leukaemia is driven by dysregulation of epigenetic regulators like NuRD, leading to reprogramming of gene regulatory networks from B lymphoid to myeloid.

bioRxiv · Jul 16, 2021Cancer Biology

JAG1-NOTCH4 MECHANOSENSING DRIVES ATHEROSCLEROSIS

C. Souilhol, X. Li, L. Canham, H. Roddie, D. Pirri, B. Tardajos Ayllon, E. Chambers, M. Dunning, M. Ariaans, J. Li, Y. Fang, M. FRAGIADAKI, V. Ridger, J. Serbanovic-Canic, S. De Val, , P. Evans

This study shows JAG1-NOTCH4 signaling promotes atherosclerosis by repressing endothelial repair in response to low oscillatory shear stress.

bioRxiv · May 15, 2020Pathology

β1 integrin is a sensor of blood flow direction

I. Xanthis, C. Souilhol, J. Serbanovic-Canic, H. Roddie, A. Kalli, M. Fragiadaki, R. Wong, D. Shah, J. Askari, L. Canham, N. Akhtar, S. Feng, V. Ridger, J. Waltho, E. Pinteaux, , P. Evans

This study identifies β1 integrin as a sensor for blood flow direction in endothelial cells, showing it is activated by unidirectional but not bidirectional shear stress.

bioRxiv · Jan 3, 2019Cell Biology

Divergent methyl-coenzyme M reductase genes in a deep-subseafloor Archaeoglobi

J. Boyd, S. Jungbluth, A. Leu, P. Evans, B. Woodcroft, G. Chadwick, V. Orphan, J. Amend, M. Rappe, G. Tyson

This study identifies a new Archaeoglobi lineage with divergent MCR genes, expanding the known evolutionary history of methane-generating archaea.

bioRxiv · Aug 13, 2018Microbiology

Neutrophil microvesicles drive atherosclerosis by delivering miR-155 to atheroprone endothelium.

I. Gomez, B. Ward, C. Souilhol, C. Recarti, M. Ariaans, J. Johnston, A. Burnett, M. Mahmoud, L. A. Luong, L. West, M. Long, S. Parry, R. Woods, C. Hulston, B. Benedikter, , V. Ridger

The paper shows neutrophil microvesicles deliver miR-155 to atheroprone endothelium, promoting vascular inflammation and atherosclerosis in mice.

bioRxiv · May 24, 2018Cell Biology