J. Duran

A mechanism that transduces lysosomal damage signals to stress granule formation for cell survival

The paper identifies a calcium-dependent pathway involving ALIX that links lysosomal damage to stress granule formation, promoting cell survival in response to various stressors.

Recent land use and land cover pressures on Iberian peatlands

This study analyzes land use and land cover changes in Iberian peatlands using historical data and environmental models to identify factors driving changes and conservation needs.

The Small GTPase Rab7 Regulates Release of Mitochondria in Extracellular Vesicles in Response to Lysosomal Dysfunction

The paper shows that Rab7 regulates mitochondrial release in extracellular vesicles when lysosomal function is impaired, and this process occurs in cardiac pathophysiology.

The global distribution and environmental drivers of the soil antibiotic resistome

This study maps the global distribution of antibiotic resistance genes in soils and identifies key environmental drivers influencing their prevalence.

Oocytes maintain ROS-free mitochondrial metabolism by suppressing complex I

This study shows that oocytes suppress complex I in mitochondria to avoid ROS production, maintaining cellular fitness and longevity.

Adult Stem Cell-derived Complete Lung Organoid Models Emulate Lung Disease in COVID-19

This study develops a human lung organoid model to emulate COVID-19 pathogenesis, showing proximal airway cells drive viral infection while distal cells drive excessive immune response.

Lack of astrocytic glycogen alters synaptic plasticity but not seizure susceptibility

GORASPs link Golgi cisternae laterally to stabilize the rims and prevent vesiculation

This study shows that GORASPs link Golgi cisternae laterally, stabilizing rims and preventing vesiculation in mice.