K. Mukherjee

RNA Binding of Syntaxin 5 Synergises Membrane Fusion to Accelerate miRNA Export and Clear Pathogens

This paper identifies Syntaxin5's role in miRNA export and pathogen clearance by showing its RNA-binding and SNARE domain functions in macrophages.

Biomechanical comparison of plate materials and designs for subcondylar fracture fixation: An in silico assessment

This study compares plate materials and designs for subcondylar fracture fixation using finite element analysis, finding that double mini plates and titanium alloys provide the best stability.

HuR-miRNA complex Activates RAS GTPase RalA to Facilitate Endosome Targeting and Extracellular Export of miRNAs

The paper develops an in vitro assay to study miRNA packaging into endosomes and shows that HuR-miRNA complexes activate RalA GTPase to facilitate miRNA import and export.

Transposon-derived transcription factors across metazoans

The paper identifies 788 transposon-derived transcription factors across metazoans, showing their recruitment in multiple phyla and lineage-specific expansions.

Biomechanical influence of plate configurations on mandible subcondylar fracture fixation: a finite element study

This study compares the biomechanical performance of five plate configurations for subcondylar fracture fixation under different mastication conditions, finding that double mini and trapezoid plates perform better.

Truncated suPAR simultaneously causes kidney disease and autoimmune diabetes mellitus

The paper identifies a truncated suPAR fragment, D2D3, that causes kidney disease and autoimmune diabetes by impairing pancreatic beta-cell function and kidney health.

Leishmania Hijacks microRNA Import-Export Machinery of Infected Macrophage and Survives by Cross-Communicating Host miR-146a to Subjugate HuR and miR-122 in Neighbouring cells

This study shows Leishmania manipulates host miRNA transport to suppress inflammation and promote its survival by exporting miR-146a and inhibiting miR-122 in neighboring cells.

Lipid Droplets Promote Phase Separation of Ago2 to Accelerate Dicer1 Loss and Decelerate miRNA Activity in Lipid Exposed Hepatic Cells

The paper shows lipid droplets promote Ago2 phase separation, reduce Dicer1 levels, and decrease miR-122 activity in hepatic cells under lipotoxic stress.

Robust expression of LINE-1 retrotransposon encoded proteins in oral squamous cell carcinoma

The paper develops a novel antibody to detect L1ORF2p, showing its expression in murine germ tissues and human oral squamous cell carcinoma samples.

A Highly Sensitive Fluorogenic Assay for the Detection of Nephrotoxin-Induced Oxidative Stress in Live Cells and Renal Tissue

This paper develops a fluorogenic assay to detect oxidative stress in live cells and renal tissue, showing improved sensitivity for identifying early signs of nephrotoxicity.