Author

L. Galbraith

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 4 Approach:experimental assay· 4 Organism:human· 3 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Organism:mouse· 1

Frequent Co-Authors

K. Blyth· 4 shared A. Roman-Fernandez· 3 shared E. Sandilands· 3 shared H. Y. Leung· 3 shared L. McGarry· 3 shared R. Patel· 3 shared S. Mason· 3 shared D. M. Bryant· 2 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersCancer Biology

K. Blyth

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4 papers

Recent·Most cited

Loss of ARID1A accelerates prostate tumourigenesis with a proliferative collagen-poor phenotype through co-operation with AP1 subunit cFos

A. Hartley, L. Galbraith, R. Shaw, A. Tibbo, R. Veeratterapillay, L. Wilson, R. Heer, K. Blyth, H. Leung, I. Ahmad

This study identifies Arid1a loss as a driver of aggressive prostate cancer in mice, accelerating tumorigenesis and promoting a proliferative, collagen-poor phenotype through cooperation with cFos.

bioRxiv · Jun 7, 2024Cancer Biology

Spatial regulation of the glycocalyx component Podocalyxin is a switch for pro-metastatic function

A. Roman-Fernandez, M. Mansour, F. G. Kugeratski, J. Anand, E. Sandilands, L. Galbraith, K. Rakovic, E. C. Freckmann, E. M. Cumming, J. Park, K. Nikolatou, S. Lilla, R. Shaw, D. Strachan, S. Mason, , D. M. Bryant

This study identifies PODXL as a decoy receptor for GAL3, revealing its role in promoting metastasis through integrin-based invasion and differential cortical targeting regulated by ubiquitination.

bioRxiv · Nov 4, 2022 · PreprintCell Biology

The small GTPase ARF3 controls metastasis and invasion modality by regulating N-cadherin levels.

E. Sandilands, E. C. Freckmann, A. Roman-Fernandez, L. McGarry, L. Galbraith, S. Mason, R. Patel, J. Anand, J. Cartwright, H. Y. Leung, K. Blyth, D. M. Bryant

This study identifies ARF3 as a regulator of invasion modality and metastasis in prostate cancer by controlling N-cadherin levels.

bioRxiv · Apr 25, 2022Cell Biology

Spatial enrichment of phosphoinositide metabolism is a molecular switch to promote metastasis.

M. Nacke, E. Sandilands, K. Nikolatou, A. Roman-Fernandez, S. Mason, R. Patel, S. Lilla, T. Yelland, L. Galbraith, L. McGarry, J. P. Morton, E. Shanks, H. Y. Leung, S. Zanivan, S. Ismail, , D. Bryant

This study identifies IQSEC1 variants that spatially regulate phosphoinositide metabolism to switch cell behavior from growth to invasion, with implications for metastasis.

bioRxiv · Sep 22, 2020 · PreprintCancer Biology