Author

M. Aikawa

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cell Biology· 1 Immunology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Research Focus:differential expression· 4 Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Assay:proteomics· 2 Assay:scRNA-seq· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

E. Aikawa· 2 shared M. C. Blaser· 2 shared M. E. Turner· 2 shared S. A. Singh· 2 shared T. Pham· 2 shared A. C. Sonawane· 1 shared A. Daugherty· 1 shared A. E. Birsner· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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2 shared papersImmunology

E. Aikawa

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Interplay Between FoxM1 and Dab2 Promotes Endothelial Cell Responses in Diabetic Wound Healing

S. Bhattacharjee, J. Gao, Y. W. Lu, S. Eisa-Beygi, H. Wu, K. S. Li, A. E. Birsner, S. Wong, Y. Song, J. Y.-J. Shyy, D. B. Cowan, W. Wei, M. Aikawa, J. Shi, H. Chen

This study identifies Dab2 and FoxM1 as key regulators of endothelial dysfunction in diabetes, showing that restoring Dab2 improves angiogenesis and wound healing.

bioRxiv · Feb 7, 2024 · PreprintCell Biology

Single-cell T cell receptor sequencing of paired tissue and blood samples reveals clonal expansion of CD8+ effector T cells in patients with calcific aortic valve disease

F. Bartoli-Leonard, S. Chelvanambi, T. Pham, M. E. Turner, M. C. Blaser, M. Caputo, M. Aikawa, A. Pang, J. Muehlschlegel, E. Aikawa

The paper uses single-cell T cell receptor sequencing to analyze paired tissue and blood samples from CAVD patients, identifying clonal expansion of CD8+ effector T cells and potential epitope targets in the valve.

bioRxiv · Jul 8, 2023 · PreprintImmunology

Intracellular Proteomics and Extracellular Vesiculomics as a Metric of Disease Recapitulation in 3D Bioprinted Aortic Valve Arrays

C. L. Clift, M. C. Blaser, W. Gerrits, M. E. Turner, A. C. Sonawane, T. Pham, J. L. Andresen, O. S. Fenton, J. M. Grolman, F. Buffolo, F. J. Schoen, J. Hjortnaes, J. D. Muehlschlegel, D. D. Mooney, M. Aikawa, , E. Aikawa

This study compares 3D-bioprinted and 2D models of calcific aortic valve disease using proteomics and vesiculomics to assess disease recapitulation.

bioRxiv · Jun 22, 2023Bioengineering

Second Heart Field-derived Cells Contribute to Angiotensin II-mediated Ascending Aortopathies

H. Sawada, Y. Katsumata, H. Higashi, C. Zhang, Y. Li, S. Morgan, L. H. Lee, S. A. Singh, J. Z. Chen, D. A. Howatt, J. J. Moorleghen, M. K. Franklin, D. L. Rateri, Y. H. Shen, S. A. LeMaire, , A. Daugherty

This study shows SHF-derived cells contribute to AngII-induced ascending aortic pathologies through LRP1 and TGF-β signaling, increasing PAI1 expression.

bioRxiv · Feb 2, 2020Pathology