Author

M. Cain

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pathology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:C. elegans· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Research Focus:metabolism & bioenergetics· 1 Organism:rat· 1

Frequent Co-Authors

A. Casimiro-Garcia· 1 shared A. Kar· 1 shared B. G. Johnson· 1 shared B. Herron· 1 shared B. L. Kennedy· 1 shared B. Zhang· 1 shared F. J. Schlerman· 1 shared H. Lin· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperPharmacology & Toxicology

A. Casimiro-Garcia

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Author profile →

2 papers

Recent·Most cited

Inhibition of ATR Reverses a Mitochondrial Respiratory Insufficiency

M. B. Borror, M. Girotti, A. Kar, M. Cain, X. Gao, V. MacKay, B. Herron, S. Bhaskaran, S. Becerra, N. Novy, N. Ventura, T. E. Johnson, B. L. Kennedy, S. L. Rea

This study shows that inhibiting ATR in C. elegans reduces the severity of mitochondrial ETC dysfunction by reversing nucleotide imbalances and restoring translation.

Cells · May 24, 2022Peer-reviewedPathology

Pharmacologic inhibition of Protein Kinase C α and Protein Kinase C β halts renal function decline indirectly, by blunting hyperphagia, and directly reduces adiposity in the ZSF1 rat model of type 2 diabetes

J. Wang, A. Casimiro-Garcia, B. G. Johnson, J. Duffen, M. Cain, L. Savary, S. Wang, P. Nambiar, M. Lech, S. Zhao, L. Xi, Y. Zhan, J. Olson, J. A. Stejskal, H. Lin, , K. Dower

The paper evaluates a PKC inhibitor in a T2D rat model, finding it halts renal decline indirectly via reduced hyperphagia and directly lowers adiposity.

bioRxiv · Dec 2, 2020 · PreprintPharmacology & Toxicology