Author

M. Major

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:development & morphogenesis· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Organism:Drosophila· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

D. Goldfarb· 2 shared A. J. Bock· 1 shared B. Bowman· 1 shared B. Weissman· 1 shared C. Hardie· 1 shared C. Huang· 1 shared C. Paiboonrungruang· 1 shared C. T. Ho· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersCell Biology

D. Goldfarb

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Small Molecule Screen Identifies Pyrimethamine as an Inhibitor of NRF2-driven Esophageal Hyperplasia

C. Paiboonrungruang, Z. Xiong, D. Lamson, Y. Li, B. Bowman, J. Chembo, C. Huang, J. Li, E. W. Livingston, J. E. Frank, V. Chen, Y. Li, B. Weissman, H. Yuan, K. P. Williams, , X. Chen

This study identifies pyrimethamine as an NRF2 inhibitor that suppresses esophageal hyperplasia in a mouse model and shows potential for clinical use in NRF2-high ESCC.

Redox Biology · Nov 1, 2023Peer-reviewedCancer Biology

The TRIM9/TRIM67 neuronal interactome reveals novel activators of morphogenesis

S. L. Menon, D. Goldfarb, C. T. Ho, E. W. Cloer, N. P. Boyer, C. Hardie, A. J. Bock, E. C. Johnson, J. Anil, M. Major, S. L. Gupton

This study identifies novel interactors of TRIM9 and TRIM67 using BioID and validates their roles in neuronal morphogenesis and axonal dynamics.

Molecular Biology of the Cell · Feb 15, 2021Peer-reviewedCell Biology

Wnt Regulation: Exploring Axin-Disheveled interactions and defining mechanisms by which the SCF E3 ubiquitin ligase is recruited to the destruction complex

K. Schaefer, M. Pronobis, C. Williams, S. Zhang, L. Bauer, D. Goldfarb, F. Yan, M. Major, M. Peifer

The paper investigates Wnt signaling by examining Axin-Dishevelled interactions and the recruitment of the SCF E3 ubiquitin ligase to the destruction complex, revealing dynamic roles of Axin and Dishevelled.

bioRxiv · Nov 20, 2019Cell Biology