Author

N. Chu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Research Focus:chromatin & epigenetic regulation· 1 Organism:human· 1 Organism:mouse· 1 Assay:protein structure· 1 Assay:proteomics· 1 Organism:zebrafish· 1

Frequent Co-Authors

A. Salguero· 1 shared B. Cai· 1 shared C. Biswas· 1 shared C. Jiang· 1 shared E. Elliott· 1 shared E. M. Behrens· 1 shared E. Park· 1 shared G. Ford· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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1 shared paperBiochemistry

A. Salguero

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Transcription Factor NRF2 is Activated by Erythrophagocytosis of Oxidized Red Blood Cell Products and Suppresses the IL-12-IFNg-IL-10 Axis in a Murine Model of Hyperinflammatory Disease

P. M. Gallo, E. Elliott, G. Ford, C. Biswas, J. Kim, J. Wheaton, C. Jiang, N. Chu, P. A. Kreiger, M. P. Lambert, E. M. Behrens

This study shows that NRF2 activation by erythrophagocytosis suppresses the IL-12-IFNg-IL-10 axis, reducing hyperinflammation in a murine model of hyperinflammatory disease.

bioRxiv · Dec 12, 2023 · PreprintImmunology

PH Domain-Mediated Autoinhibition and Oncogenic Activation of Akt

H. Bae, T. Viennet, E. Park, N. Chu, A. Salguero, M. J. Eck, H. Arthanari, P. A. Cole

This study identifies a mutation in the PH domain of Akt that enhances autoinhibition and reveals the molecular mechanism of Akt activation as an oncogenic driver.

bioRxiv · May 25, 2022Biochemistry

Moxifloxacin efficacy against Mycobacterium abscessus in vivo using zebrafish model

W. Nie, S. Gao, T. Teng, W. Zhou, Y. Shang, W. Jing, W. Shi, Q. Wang, X. Huang, B. Cai, J. Wang, J. Wang, R. Guo, Q. Ge, L. Nie, , N. Chu

This study evaluates moxifloxacin efficacy against Mycobacterium abscessus in a zebrafish model, finding limited in vivo activity despite good in vitro results.

bioRxiv · Dec 5, 2019 · PreprintMicrobiology