R. D. Smith

Phosphorylation barcodes direct biased chemokine signaling at CXCR3

The paper shows that CXCR3 chemokines use different phosphorylation barcodes to activate distinct signaling pathways, leading to varied physiological outcomes.

A streamlined tandem tip-based workflow for sensitive nanoscale phosphoproteomics

This paper introduces a streamlined phosphoproteomics workflow that reduces sample loss and processing time, enabling sensitive detection of phosphopeptides from nanoscale samples.

MgrB dependent colistin resistance in Klebsiella pneumoniae is associated with an increase in host-to-host transmission.

This study shows that MgrB-dependent colistin resistance in K. pneumoniae reduces gut colonization but increases survival outside the host, enhancing transmission.

Robotic Multi-Probe-Single-Actuator Inchworm Neural Microdrive

This paper introduces a robotic multi-probe-single-actuator neural microdrive using phase-change-material micro-grippers for precise electrode placement in rat hippocampus.

An Essential Role for Argonaute 2 in EGFR-KRAS Signaling in Pancreatic Cancer Development

This study shows AGO2 is required for pancreatic cancer progression but not initiation, with its role dependent on mutant KRAS and EGFR signaling.

Mechanisms driving endosperm-based hybrid incompatibilities: insights from hybrid monkeyflowers

This study investigates genomic imprinting and epigenetic changes in hybrids of Mimulus guttatus and M. luteus, revealing altered methylation and expression patterns that contribute to endosperm-based hybrid incompatibilities.

Proximity-dependent proteomics of the Chlamydia trachomatis inclusion membrane reveals functional interactions with endoplasmic reticulum exit sites

This study uses proximity-dependent biotinylation to identify inclusion membrane proteins of Chlamydia trachomatis and reveals a novel interaction with endoplasmic reticulum exit sites.