R. Nanda

Lung Mycobacterium tuberculosis infection perturbs metabolic pathways in non-pulmonary tissues

This study shows that Mtb infection alters amino acid metabolism in non-pulmonary tissues of mice, with age-specific metabolic changes observed in different tissue types.

Hypothetical gene Rv0495c regulates redox homeostasis in Mycobacterium tuberculosis

This study identifies Rv0495c as a regulator of redox homeostasis in Mtb, showing that its absence increases ROS and susceptibility to stress, yet enhances pathogenicity in host models.

Deferoxamine as adjunct therapeutics for tuberculosis

This study shows Deferoxamine (DFO) has antimycobacterial properties and can reduce Mtb burden when used as an adjunct to standard tuberculosis treatments.

Host immunosenescence compromises Mycobacterium tuberculosis clearance

This study shows that immunosenescence in older mice impairs Mycobacterium tuberculosis clearance, linked to mitochondrial dysfunction and altered immune cell responses.

Dysregulated cysteine metabolism leads to worsened liver pathology in diabetes-tuberculosis comorbid mice.

This study identifies dysregulated cysteine and retinol metabolism in diabetic-tuberculosis comorbid mice as contributors to worsened liver pathology.

Multimodal Prediction of Breast Cancer Recurrence Assays and Risk of Recurrence

This paper develops a deep learning model that predicts breast cancer recurrence using digital histology and clinical factors, outperforming a clinical nomogram and identifying patients who may avoid genomic testing.

Acute radiofrequency electromagnetic radiation exposures cause neuronal DNA damage and impair neurogenesis in the young adolescent rat brain

This study shows that acute RF-EMR exposure in adolescent rats causes DNA damage and impairs neurogenesis in the hippocampus.

Troxerutin acts on complement mediated inflammation to ameliorate arthritic symptoms in rats.

This study shows that troxerutin reduces arthritis symptoms in rats by modulating complement-mediated inflammation.

RRBP1 rewires cisplatin resistance in Oral Squamous Cell Carcinoma by regulating YAP-1

This study identifies RRBP1 as a key regulator of cisplatin resistance in OSCC, showing its role in YAP-1 regulation and demonstrating that Radezolid can restore cisplatin sensitivity.

Anti-inflammatory role of curcumin in Lipopolysaccharide treated A549 cells at global proteome level and on mycobacterial infection

This study uses proteomics to show curcumin reduces inflammation and bacterial load in LPS-treated A549 cells by modulating mitochondrial proteins and neutralizing LPS effects.

Untargeted metabolite analysis of Ocimum leaves shows species specific variations

This study performs untargeted metabolite analysis of Ocimum species leaves to identify species-specific variations using GC-MS.

Diurnal variations in serum metabolites of wintering redheaded buntings.

The paper examines diurnal metabolite variations in redheaded buntings, finding higher daytime lipid and protein catabolites and night-time short chain fatty acids and taurine, suggesting differential energy use during migration.