Author

M. Netea

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 6 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 6 Research Focus:host-pathogen & immune response· 5 Approach:experimental assay· 4 Research Focus:cell type annotation· 2 Assay:proteomics· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

L. A. Joosten· 2 shared L. B. Barreiro· 2 shared M. Divangahi· 2 shared A. Costa· 1 shared A. Dumaine· 1 shared A. Hoischen· 1 shared A. Larbi· 1 shared A. Lee· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 11 mutual co-author links

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2 shared papersImmunology

L. A. Joosten

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

BCG vaccination impacts the epigenetic landscape of progenitor cells in human bone marrow

S. J. Sun, R. Aguirre-Gamboa, C. J. de Bree, J. Sanz, A. Dumaine, L. A. Joosten, M. Divangahi, M. Netea, L. B. Barreiro

This study shows BCG vaccination changes gene expression and chromatin accessibility in human bone marrow progenitor cells, linking these changes to innate immune responses.

bioRxiv · Nov 28, 2023 · PreprintImmunology

Multi-omic profiling of pathogen-stimulated primary immune cells

R. Salz, E. E. Vorsteveld, C. I. van der Made, S. Kersten, M. Stemerdink, T. Hsieh, M. Mhlanga, M. Netea, P.-J. Volders, A. Hoischen, P. A. C. 't Hoen

The paper uses long-read sequencing to profile immune cells stimulated by pathogens, identifying novel transcripts and isoforms that reveal new insights into immune response mechanisms.

bioRxiv · Sep 13, 2023Immunology

HIV-linked gut dysbiosis associates with cytokine production capacity in viral-suppressed people living with HIV

Y. Zhang, S. Andreu-Sanchez, N. Vadaq, D. Wang, V. Matzaraki, W. van der Heijden, R. Gacesa, R. K. Weersma, A. Zhernakova, L. Vandekerckhove, Q. de Mast, L. A. Joosten, M. Netea, A. van der Ven, J. Fu

This study links HIV-associated gut dysbiosis to cytokine production capacity in ART-suppressed PLHIV, identifying specific microbial strains associated with immune markers.

bioRxiv · Apr 21, 2022 · PreprintMicrobiology

Lung epithelial signaling mediates early vaccine-induced CD4+ T cell activation and Mtb control

S. Das, N. D. Marin, E. Esaulova, M. Ahmed, A. Swain, B. A. Rosa, M. Mitreva, J. Rangel-Moreno, M. Netea, L. B. Barreiro, M. Divangahi, M. Artyomov, D. Kaushal, S. A. Khader

This study identifies lung epithelial signaling as critical for early vaccine-induced CD4+ T cell activation and Mtb control in BCG vaccinated hosts.

bioRxiv · Jun 3, 2021Immunology

The Immunological Factors Predisposing To Severe COVID-19 Are Already Present In Healthy Elderly And Men

G. Kilic, O. Bulut, M. Jaeger, R. ter Horst, V. Koeken, S. J. C. F. M. Moorlag, V. Mourits, C. de Bree, J. Dominguez-Andres, L. A. B. Joosten, M. Netea

The paper identifies immunological factors associated with severe COVID-19 in healthy elderly and men, showing intrinsic differences in immune cell subsets and inflammatory proteins.

bioRxiv · Apr 30, 2021Immunology

Metformin enhances anti-mycobacterial responses by educating immunometabolic circuits of CD8+ T cells

J. Bohme, N. Martinez, S. Li, A. Lee, M. Marzuki, A. Tizazu, D. Ackart, J. Frenkel, A. Todd, E. Lachmandas, J. Lum, F. Shihui, T. P. Ng, B. Lee, A. Larbi, , A. Singhal

This study shows metformin improves anti-mycobacterial responses by enhancing metabolic and functional properties of CD8+ T cells in mice and humans.

bioRxiv · Aug 26, 2020Immunology

The right microbial stimulus can direct innate immune effector cells to specific organ sites to clear pathology

S. Kalyan, M. Bazett, H. P. Sham, M. Bosiljcic, B. Luk, S. Dhanji, A. Costa, S. Wong, M. Netea, D. Mullins, H. Gunn

This paper demonstrates that microbial-based stimuli can direct innate immune effector cells to specific organs to clear pathology, independent of the disease type.

bioRxiv · Apr 17, 2019 · PreprintImmunology