Author

S.-J. Park

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 3 Microbiology· 2 Biochemistry· 1 Bioengineering· 1 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Approach:experimental assay· 4 Assay:structural biology· 4 Approach:statistical model· 3 Organism:virus· 3 Approach:deep learning· 2 Research Focus:differential expression· 2 Assay:DNA methylation· 2

Frequent Co-Authors

W. Im· 4 shared Y. K. Choi· 4 shared C. Seok· 3 shared H. Woo· 3 shared M. S. Yeom· 3 shared Y. Cao· 3 shared M. Frank· 2 shared T. I. Croll· 2 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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Curved chords = mutual co-authorship

4 shared papersBiophysics

W. Im

Mutual co-authors in cluster

Author profile →

9 papers

Recent·Most cited

Structural modeling of cytokine-receptor-JAK2 signaling complexes using AlphaFold Multimer

I. D. Pogozheva, S. Cherepanov, S.-J. Park, M. Raghavan, W. Im, A. Lomize

The paper uses AlphaFold Multimer to model cytokine-receptor-JAK2 signaling complexes, revealing activation mechanisms and oncogenic mutation impacts.

bioRxiv · Jun 14, 2023 · PreprintBiochemistry

Rickettsiales' deep evolutionary history sheds light on the emergence of intracellular lifestyles

L. Serra Moncadas, T. Shabarova, V. Silva Kavagutti, P.-A. Bulzu, M.-C. Chiriac, S.-J. Park, I. Mukherjee, R. Ghai, A.-S. Andrei

This study investigates the evolutionary history of Rickettsiales bacteria, showing how cross-feeding interactions with eukaryotes influenced their transition to intracellular lifestyles and genomic adaptations.

bioRxiv · Jan 31, 2023 · PreprintMicrobiology

MANF stimulates autophagy and restores mitochondrial homeostasis to treat toxic proteinopathy

Y. Kim, C. Li, C. Gu, E. Tycksen, A. Puri, T. A. Pietka, J. Sivapackiam, Y. Fang, K. Kidd, S.-J. Park, B. G. Johnson, S. Kmoch, J. S. Duffield, A. J. Bleyer, M. E. Jackrel, , Y. M. Chen

This study shows that MANF improves autophagy and mitochondrial function in a mouse model of ADTKD-UMOD, offering a potential therapy for proteinopathies.

bioRxiv · Jan 10, 2023 · PreprintCell Biology

Gut microbiota analysis of the western honeybee (Apis mellifera L.) infested with the mite Varroa destructor reveals altered bacterial and archaeal community

M. Kim, W. J. Kim, S.-J. Park

This study analyzes the gut microbiota of western honeybees infected with Varroa destructor, finding altered bacterial and archaeal communities in larvae and adult bees.

bioRxiv · Apr 20, 2022 · PreprintMicrobiology

Dynamic Interactions of Fully Glycosylated SARS-CoV-2 Spike Protein with Various Antibodies

Y. Cao, Y. K. Choi, M. Frank, H. Woo, S.-J. Park, M. S. Yeom, C. Seok, W. Im

This study uses molecular dynamics simulations to analyze SARS-CoV-2 spike protein interactions with antibodies, revealing structural dynamics and mutation impacts on neutralization.

bioRxiv · May 10, 2021Biophysics

Nanoparticle Cellular Internalization is Not Required for RNA Delivery to Mature Plant Leaves

H. Zhang, N. S. Goh, J. Wang, G. S. Demirer, S. Butrus, S.-J. Park, M. P. Landry

This study shows that small spherical AuNPs can deliver siRNA efficiently to plant leaves without entering cells, challenging the need for nanoparticle internalization in RNA delivery.

bioRxiv · Mar 17, 2021Bioengineering

Single-cell Transcriptome of Bronchoalveolar Lavage Fluid Reveals Dynamic Change of Macrophages During SARS-CoV-2 Infection in Ferrets

J. S. Lee, J.-Y. Koh, K. Yi, Y.-I. Kim, S.-J. Park, E.-H. Kim, S.-M. Kim, S. H. Park, Y. S. Ju, Y. K. Choi, S.-H. Park

This study uses single-cell RNA sequencing to track macrophage dynamics in SARS-CoV-2-infected ferrets over time, revealing distinct subpopulations and functional changes.

bioRxiv · Nov 18, 2020Immunology

Structure, Dynamics, Receptor Binding, and Antibody Binding of Fully-glycosylated Full-length SARS-CoV-2 Spike Protein in a Viral Membrane

Y. K. Choi, Y. Cao, M. Frank, H. Woo, S.-J. Park, M. S. Yeom, T. I. Croll, C. Seok, W. Im

This study uses molecular dynamics simulations to analyze the structure, dynamics, and antibody binding of the fully-glycosylated SARS-CoV-2 spike protein, revealing key roles of glycans in stabilizing RBD conformations and antibody epitope exposure.

bioRxiv · Oct 18, 2020Biophysics

Developing a Fully-glycosylated Full-length SARS-CoV-2 Spike Protein Model in a Viral Membrane

H. Woo, S.-J. Park, Y. K. Choi, T. Park, M. Tanveer, Y. Cao, N. R. Kern, J. Lee, M. S. Yeom, T. I. Croll, C. Seok, W. Im

The paper models and simulates a fully-glycosylated SARS-CoV-2 spike protein in a viral membrane using computational methods and provides the structures for research on COVID-19 prevention and treatment.

bioRxiv · May 20, 2020Biophysics