Author

K. Yi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Cell Biology· 2 Evolutionary Biology· 2 Immunology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cell type annotation· 4 Approach:statistical model· 3 Research Focus:cell signaling & trafficking· 2 Approach:deep learning· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:plant (other)· 2

Frequent Co-Authors

B. Wu· 2 shared B. Zhou· 2 shared L. Hong· 2 shared L. Zheng· 2 shared M. McClain· 2 shared N. Rohner· 2 shared Y. Tan· 2 shared A. Bernal-Rivera· 1 shared

Activity by Year

2019-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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2 shared papersBioengineering

B. Wu

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Author profile →

8 papers

Recent·Most cited

Protein Engineering with Lightweight Graph Denoising Neural Networks

B. Zhou, L. Zheng, B. Wu, Y. Tan, O. Lv, K. Yi, G. Fan, L. Hong

This study introduces a lightweight graph neural network for protein engineering that predicts fitness and guides the design of effective mutants with improved physicochemical properties.

bioRxiv · Nov 5, 2023Bioengineering

A conditional protein diffusion model generates artificial programmable endonuclease sequences with enhanced activity

B. Zhou, L. Zheng, B. Wu, K. Yi, B. Zhong, Y. Tan, Q. Liu, P. Lio, L. Hong

This paper introduces CPDiffusion, a conditional protein diffusion model that generates artificial endonuclease sequences with enhanced activity without labeled data.

bioRxiv · Aug 10, 2023Bioengineering

Sugar assimilation underlying dietary evolution of Neotropical bats

J. Camacho, A. Bernal-Rivera, V. Pena, P. Morales-Sosa, S. Robb, J. Russell, K. Yi, D. Tsuchiya, Y. Wang, O. E. Murillo-Garcia, N. Rohner

This study examines sugar assimilation in Neotropical bats, revealing metabolic adaptations to different diets through glucose tolerance tests, genome analysis, and gene expression studies.

bioRxiv · Jul 2, 2023Evolutionary Biology

AIM1-dependent high basal SA accumulation modulates stomatal aperture in rice

L. Xu, H. Zhao, J. Wang, X. Wang, X. Jia, Z. Xu, R. Li, K. Jiang, Z. Chen, J. Luo, X. Xie, K. Yi

This study identifies OsAIM1 as essential for high basal SA levels in rice, which regulate stomatal aperture and shoot temperature.

bioRxiv · Jun 23, 2022 · PreprintPlant Biology

Metabolic reprogramming underlies cavefish muscular endurance despite loss of muscle mass and contractility

L. Olsen, M. Levy, J. K. Medley, H. Hassan, R. Alexander, E. Wilcock, K. Yi, L. Florens, S. McKinney, R. Peuss, J. Persons, A. Kenzior, E. Maldonado, A. Gluesenkamp, E. Mager, , N. Rohner

This paper shows cavefish have reduced muscle mass and contractility but increased muscular endurance due to metabolic reprogramming involving glycogen utilization.

bioRxiv · Mar 12, 2022Evolutionary Biology

Single-cell Transcriptome of Bronchoalveolar Lavage Fluid Reveals Dynamic Change of Macrophages During SARS-CoV-2 Infection in Ferrets

J. S. Lee, J.-Y. Koh, K. Yi, Y.-I. Kim, S.-J. Park, E.-H. Kim, S.-M. Kim, S. H. Park, Y. S. Ju, Y. K. Choi, S.-H. Park

This study uses single-cell RNA sequencing to track macrophage dynamics in SARS-CoV-2-infected ferrets over time, revealing distinct subpopulations and functional changes.

bioRxiv · Nov 18, 2020Immunology

The wtf4 meiotic driver utilizes controlled protein aggregation to generate selective cell death

N. L. Nuckolls, A. C. Mok, J. J. Lange, K. Yi, T. S. Kandola, A. M. Hunn, S. McCroskey, J. L. Snyder, M. A. Bravo Nunez, M. McClain, S. A. McKinney, C. Wood, R. Halfmann, S. E. Zanders

This study shows that the wtf4 meiotic driver uses protein aggregation and sequestration to selectively kill cells, revealing a mechanism for meiotic drive.

bioRxiv · Feb 5, 2020Cell Biology

Subcellular analyses of planarian meiosis implicates a novel, double-membraned vesiculation process in nuclear envelope breakdown

L. Guo, F. Guo, S. Zhang, K. Yi, M. McClain, C.-D. Kuhn, T. Parmely, A. Sanchez Alvarado

The paper identifies a novel double-membraned vesiculation process in planarian oocytes during nuclear envelope breakdown, revealing evolutionary adaptability of NEBD.

bioRxiv · May 5, 2019 · PreprintCell Biology