Synthesis and Assembly of a New-generation Bifunctional Lipid Nanoparticle for Selective Delivery of mRNA to Antigen Presenting Cells
C.-Y. Chen, S.-W. Wang, C.-H. Wong
This paper develops a new mRNA-BLNP3 nanoparticle that selectively delivers mRNA to antigen-presenting cells, showing improved immune responses and reduced liver accumulation compared to previous versions.
bioRxiv · Dec 26, 2023 · PreprintBiochemistry