Author

T.-H. Chen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4 Bioengineering· 1 Cancer Biology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:host-pathogen & immune response· 4 Organism:human· 3 Research Focus:drug response / drug discovery· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

C. Ma· 3 shared A. Townsend· 2 shared C.-G. Huang· 2 shared C.-P. Chen· 2 shared C.-Y. Cheng· 2 shared J.-T. Jan· 2 shared K.-Y. A. Huang· 2 shared M. Knight· 2 shared

Activity by Year

2020-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersMicrobiology

C. Ma

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Nanofluid-Enhanced Laser Lithotripsy Using Conducting Polymer Nanoparticles

Q. Fan, J. Chen, A. Mishra, A. Stewart, F. Anees, J. Dominguez, T.-H. Chen, C. Payne, M. Lipkin, P. Zhong, P.-C. Hsu

This paper enhances laser lithotripsy efficiency using a PEDOT:PSS nanofluid, achieving significant improvements in stone ablation without increased thermal injury.

bioRxiv · Jun 1, 2024Bioengineering

A 3D in vitro assay to study combined immune cell infiltration and cytotoxicity

A. J. Crawford, A. Johnston, W. Du, E. A. Hanna, D. Schell, Z. Wan, T.-H. Chen, F. Wu, K. Ren, Y. Lim, P. R. Nair, D. Wirtz

This paper introduces a 3D in vitro assay to study immune cell infiltration and cytotoxicity in solid tumors, showing it captures key steps of immune cell interaction with the tumor microenvironment.

bioRxiv · Mar 27, 2024 · PreprintCancer Biology

Impact of glycosylation on a broad-spectrum vaccine against SARS-CoV-2

H.-Y. Huang, H.-Y. Liao, X. Chen, S.-W. Wang, C.-W. Cheng, M. Shahed-Al-Mahmud, T.-H. Chen, J. M. Lo, Y.-M. Liu, Y.-M. Wu, H.-H. Ma, Y.-H. Chang, H.-Y. Tsai, Y.-C. Chou, Y.-P. Hsueh, , C.-H. Wong

This study shows that trimming N-glycans from the SARS-CoV-2 spike protein enhances immune responses and protection against variants in hACE2 mice.

bioRxiv · May 25, 2021 · PreprintMicrobiology

Expression of human ACE2 N-terminal domain, part of the receptor for SARS-CoV-2, in fusion with maltose binding protein, E. coli ribonuclease I and human RNase A

S.-y. Xu, A. Fomenkov, T.-H. Chen, E. Yigit

This paper constructs and evaluates RNase fusion proteins with the human ACE2 N-terminal domain to degrade SARS-CoV-2 RNA in vitro.

bioRxiv · Jan 31, 2021 · PreprintMicrobiology

Plasmablast-derived antibody response to acute SARS-CoV-2 infection in humans

K.-Y. A. Huang, T. Tan, T.-H. Chen, C.-G. Huang, R. Harvey, S. Hussain, C.-P. Chen, A. Harding, J. Gilbert-Jaramillo, X. Liu, M. Knight, L. Schimanski, S.-R. Shih, Y.-C. Lin, C.-Y. Cheng, , A. Townsend

This study analyzes plasmablast-derived antibodies in three COVID-19 patients, identifying neutralizing antibodies and cross-reactivity with other betacoronaviruses.

bioRxiv · Aug 28, 2020 · PreprintMicrobiology

Impact of urolithiasis and hydronephrosis on acute kidney injury in patients with urinary tract infection

C.-Y. Hsiao, T.-H. Chen, Y.-C. Lee, M.-C. Wang

This study examines the impact of urolithiasis and hydronephrosis on acute kidney injury in patients with urinary tract infection, finding that ureteral stones with hydronephrosis significantly increase AKI risk.

bioRxiv · Jul 13, 2020 · PreprintPathology

Structural basis for the neutralization of SARS-CoV-2 by an antibody from a convalescent patient

D. Zhou, H. M. E. Duyvesteyn, C.-P. Chen, C.-G. Huang, T.-H. Chen, S.-R. Shih, Y.-C. Lin, C.-Y. Cheng, S.-H. Cheng, Y.-C. Huang, T.-Y. Lin, C. Ma, J. Huo, L. Carrique, T. Malinauskas, , K.-Y. A. Huang

This paper identifies an antibody, EY6A, from a convalescent patient that neutralizes SARS-CoV-2 and cross-reacts with SARS-CoV-1 by binding a conserved epitope on the Spike protein.

bioRxiv · Jun 12, 2020Microbiology