Author

T. Hato

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Physiology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 4 Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Research Focus:host-pathogen & immune response· 2

Frequent Co-Authors

D. Janosevic· 3 shared J. Myslinski· 3 shared P. C. Dagher· 3 shared K. Banno· 2 shared X. Xuei· 2 shared Y. Liu· 2 shared A. Bopda Waffo· 1 shared A. Halim· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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3 shared papersPhysiology

D. Janosevic

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Dynamic Single Cell Transcriptomics Defines Kidney FGF23/KL Bioactivity and Novel Segment-Specific Inflammatory Targets

R. Agoro, J. Myslinski, Y. G. Marambio, D. Janosevic, K. N. Jennings, S. Liu, L. M. Hibbard, F. Fang, P. Ni, M. L. Noonan, E. Solis, X. Chu, Y. Wang, P. C. Dagher, Y. Liu, , K. White

This study uses single-cell transcriptomics to analyze FGF23 bioactivity and identify novel inflammatory targets in the kidney, revealing interactions between FGF23 and TNF/NF-κB pathways.

bioRxiv · May 24, 2024Physiology

miRNA and mRNA Signatures in Human Acute Kidney Injury Tissue

D. Janosevic, T. De Luca, R. M. Ferreira, D. L. Gisch, T. Hato, J. Luo, Y. Yang, J. B. Hodgin, P. C. Dagher, M. T. Eadon

This study identifies miRNA and mRNA signatures in human AKI tissue, revealing their roles in inflammation, immune activation, and epithelial-to-mesenchymal transition, and highlights the importance of using appropriate reference controls.

bioRxiv · Sep 11, 2023Cell Biology

Origin, Prospective Identification, and Function of Circulating Endothelial Colony Forming Cells in Mouse and Human

Y. Lin, K. Banno, C.-H. Gil, J. Myslinski, T. Hato, W. C. Shelley, H. Gao, X. Xuei, Y. Liu, D. P. Basile, M. Yoshimoto, N. Prasain, S. P. Tarnawsky, R. H. Adams, K. Naruse, , M. C. Yoder

This study identifies the origin and function of circulating endothelial colony forming cells (C-ECFCs) in mice and humans, showing they arise from tissue-resident ECFCs and have vasculogenic potential.

bioRxiv · Jul 31, 2022 · PreprintCell Biology

Translation rescue by targeting Ppp1r15a upstream open reading frame in vivo

A. Kidwell, S. P. S. Yadav, B. Maier, A. Zollman, K. Ni, A. Halim, D. Janosevic, J. Myslinski, F. Syed, L. Zeng, A. Bopda Waffo, K. Banno, X. Xuei, E. H. Doud, P. C. Dagher, T. Hato

This study shows that targeting the Ppp1r15a upstream open reading frame rescues translation and improves kidney function in sepsis by overcoming uORF-mediated repression.

bioRxiv · Dec 11, 2021Physiology

The kidney protects against sepsis by producing systemic uromodulin

K. LaFavers, C. Hage, V. Gaur, R. Micanovic, T. Hato, S. Khan, S. Winfree, S. Doshi, R. Moorthi, H. Twigg, X.-R. Wu, P. Dagher, E. Srour, T. M. El-Achkar

This paper identifies uromodulin (THP) as a protective factor in sepsis, showing its role in enhancing mononuclear phagocyte function and reducing mortality in mice.

bioRxiv · Jan 8, 2021Immunology