Author

P. Ni

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Biophysics· 1 Evolutionary Biology· 1 Immunology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Organism:mouse· 3 Approach:deep learning· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:rat· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1

Frequent Co-Authors

B. Hu· 2 shared B. Liu· 2 shared Y. Wang· 2 shared Y. Xu· 2 shared Z. Fang· 2 shared B. Yang· 1 shared B. Zhang· 1 shared C. Wang· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersImmunology

B. Hu

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Dynamic Single Cell Transcriptomics Defines Kidney FGF23/KL Bioactivity and Novel Segment-Specific Inflammatory Targets

R. Agoro, J. Myslinski, Y. G. Marambio, D. Janosevic, K. N. Jennings, S. Liu, L. M. Hibbard, F. Fang, P. Ni, M. L. Noonan, E. Solis, X. Chu, Y. Wang, P. C. Dagher, Y. Liu, , K. White

This study uses single-cell transcriptomics to analyze FGF23 bioactivity and identify novel inflammatory targets in the kidney, revealing interactions between FGF23 and TNF/NF-κB pathways.

bioRxiv · May 24, 2024Physiology

Leveraging a large language model to predict protein phase transition: a physical, multiscale and interpretable approach

M. Frank, P. Ni, M. Jensen, M. B. Gerstein

This paper fine-tunes a large language model to predict protein phase transitions from sequence data and shows its utility in assessing sequence variants' effects on aggregation and droplet formation.

bioRxiv · Nov 21, 2023 · PreprintBiophysics

PF-D-Trimer, a broadly protective SARS-CoV-2 subunit vaccine: immunogenicity and application

Z. Zhang, J. Zhou, P. Ni, B. Hu, S. Deng, Q. Xiao, Q. He, G. Li, Y. Xia, M. Liu, C. Wang, Z. Fang, N. Xia, Z.-R. Zhang, B. Zhang, , B. Liu

This paper presents a subunit vaccine, PF-D-Trimer, derived from the Delta spike protein, showing robust immunogenicity and cross-reactive neutralizing antibodies against multiple SARS-CoV-2 variants.

bioRxiv · Sep 26, 2022Immunology

Development and application of an uncapped mRNA platform

X. Zheng, B. Liu, P. Ni, L. Cai, X. Shi, Z. Ke, S. Zhang, B. Hu, B. Yang, Y. Xu, W. Long, Z. Fang, Y. Wang, W. Zhang, Y. Xu, , B. Liu

The paper develops an uncapped mRNA platform and demonstrates its effectiveness in inducing immune responses and protein expression in vitro and in vivo.

bioRxiv · Jun 5, 2022 · PreprintBioengineering

Prevalent uses and evolution of exonic regulatory sequences in the human genome

J. Chen, P. Ni, M. Niu, J.-t. Guo, Z. Su

The paper investigates the prevalence and evolution of exonic regulatory sequences, finding that exonic TFBSs are common and may evolve into regulatory elements when non-exonic sequences are unavailable.

bioRxiv · Sep 6, 2021Evolutionary Biology