Author

T. Scriba

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 7

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 7 Assay:flow cytometry· 7 Organism:human· 6 Approach:experimental assay· 5 Research Focus:differential expression· 4 Research Focus:cell signaling & trafficking· 2 Approach:statistical model· 2 Research Focus:cell-cell communication· 1

Frequent Co-Authors

E. Nemes· 3 shared M. Hatherill· 3 shared A. Gela· 2 shared C. Seshadri· 2 shared M. Donato· 2 shared P. Khatri· 2 shared W. Hanekom· 2 shared A. C. Bohrer· 1 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersImmunology

E. Nemes

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Rapid GPR183-mediated recruitment of eosinophils to the lung after Mycobacterium tuberculosis infection

A. C. Bohrer, E. Castro, C. E. Tocheny, M. Assmann, B. Schwarz, E. Bohrnsen, M. A. Makiya, F. Legrand, K. L. Hilligan, P. J. Baker, F. Torres-Juarez, Z. Hu, H. Ma, L. Wang, L. Niu, , K. D. Mayer-Barber

This study shows that eosinophils migrate to the lungs early after Mycobacterium tuberculosis infection in mice and macaques, mediated by GPR183 and Ch25h, independent of CCR3.

bioRxiv · Feb 18, 2022Immunology

Crosstalk of Histone Modifications in the Healthy Human Immune System

D. Dermadi, L. Kalesinskas, A. Ganesan, A. Kuo, P. Cheung, S. Cheng, M. Dvorak, T. Scriba, A. Habtezion, M. Donato, P. J. Utz, P. Khatri

The paper analyzes histone post-translational modifications in human immune cells to uncover their interactions and functional implications.

bioRxiv · Jan 21, 2022 · PreprintImmunology

The role of antigen recognition in the γδ T cell response at the controlled stage of M. tuberculosis infection.

R. Roy Chowdhury, J. R. Valainis, O. Kask, M. Ohanyan, M. Sun, H. Huang, M. Dubey, L. von Boehmer, E. Sola, X. Huang, P. K. Nguyen, T. Scriba, M. M. Davis, S. C. Bendall, Y.-h. Chien

This study identifies a distinct CD8+γδ T cell population in controlled Mtb infection that exhibits NK-like cytotoxicity and stage-specific antigen recognition.

bioRxiv · Sep 14, 2021 · PreprintImmunology

Effects of BCG vaccination on donor unrestricted T cells in humans

A. Gela, M. Murphy, K. Hadley, W. Hanekom, H. Boom, J. Johnson, D. Hoft, S. Joosten, T. Ottenhoff, S. Suliman, B. Moody, D. Lewinsohn, M. Hatherill, C. Seshadri, E. Nemes, T. Scriba

This study examines the effects of BCG vaccination on donor unrestricted T (DURT) cells in humans, finding increased frequencies of certain T cell subsets in infants but no changes in others.

bioRxiv · Apr 29, 2021 · PreprintImmunology

CD4 and CD8 co-receptors modulate functional avidity of CD1b-restricted T cells.

C. A. James, Y. Xu, M. S. Aguilar, L. Jing, E. D. Layton, M. Gilleron, A. J. Minnaard, T. Scriba, C. L. Day, E. H. Warren, D. M. Koelle, C. Seshadri

This study investigates how CD4 and CD8 co-receptors affect the functional avidity and activation of CD1b-restricted T cells specific for mycobacterial lipid antigens, revealing distinct functional profiles and proliferation patterns.

bioRxiv · Oct 17, 2020Immunology

Postnatal expansion, maturation and functionality of MR1 T cells in humans

G. M. Swarbrick, A. Gela, M. E. Cansler, M. D. Null, R. B. Duncan, E. Nemes, M. Shey, M. Nsereko, H. Mayanja-Kizza, S. Kiguli, J. Koh, W. Hanekom, M. Hatherill, C. Lancioni, D. M. Lewinsohn, , D. A. Lewinsohn

This study examines the postnatal development of MR1-restricted T cells in humans, showing their expansion, maturation, and functional maturation in response to environmental exposure and tuberculosis infection.

bioRxiv · Dec 20, 2019 · PreprintImmunology

A comparison of antigen-specific T cell responses induced by six novel tuberculosis vaccine candidates

M. J. Rodo, V. Rozot, E. Nemes, O. Dintwe, M. Hatherill, F. Little, T. Scriba

This study compares antigen-specific T cell responses of six TB vaccine candidates and BCG, finding that M72/AS01E induced the strongest memory CD4 T cell responses.

bioRxiv · Oct 25, 2018Immunology