Author

Y. Nan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 3 Microbiology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:drug response / drug discovery· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1

Frequent Co-Authors

P. Zhao· 3 shared Q. Luo· 3 shared S. Liu· 3 shared W. Chang· 3 shared X. Wu· 3 shared Z. Liu· 3 shared C. Han· 1 shared C. Wu· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersCancer Biology

P. Zhao

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

m6A Demethylase FTO Stabilizes LINK-A to Exert Oncogenic Roles via MCM3-Mediated Cell Cycle Progression and HIF-1α Activation

Y. Nan, S. Liu, Q. Luo, X. Wu, P. Zhao, W. Chang, Z. Liu

This study shows FTO stabilizes LINK-A, promoting ESCC progression through MCM3-mediated cell cycle progression and HIF-1α activation.

bioRxiv · Jan 28, 2023Cancer Biology

Prion-like characteristics of Hepatitis E virus ORF3 protein are associated with virus release and pathogenesis

Y. Wang, H. Tian, N. Shi, C. Wu, Y. Huang, Y. Yang, Q. Ding, X. Zheng, Q. Zhao, M. Tuite, H. Chen, Y. Nan

This study identifies HEV-ORF3 as a prion-like protein that facilitates virion release and pathogenesis by forming filamentous structures, highlighting its role in viral assembly.

bioRxiv · Jan 13, 2023 · PreprintMicrobiology

HCP5 prevents ubiquitination-mediated UTP3 degradation to inhibit apoptosis by activating c-Myc transcriptional activity

Y. Nan, Q. Luo, X. Wu, W. Chang, P. Zhao, S. Liu, Z. Liu

This study identifies HCP5 as a key antiapoptotic factor in ESCC by preventing UTP3 degradation and activating c-Myc to suppress apoptosis.

bioRxiv · Jun 13, 2022Cancer Biology

DLGAP1-AS2-Mediated Phosphatidic Acid Synthesis Confers Chemoresistance via Activation of YAP Signaling

Y. Nan, Q. Luo, X. Wu, S. Liu, P. Zhao, W. Chang, Z. Liu

This study identifies D-AS2 as a noncoding RNA that promotes chemoresistance in SCC by activating YAP signaling through the PLD/PA axis, and shows that targeting D-AS2 sensitizes SCC to cisplatin.

bioRxiv · Feb 24, 2022Cancer Biology

Combining Multi-Dimensional Molecular Fingerprints to Predict hERG Cardiotoxicity of Compounds

W. Ding, L. Zhang, Y. Nan, J. Wu, X. Xin, C. Han, S. Li, H. Liu

This study develops a molecular dynamic fingerprint (MDFP) and combines it with traditional fingerprints to predict hERG cardiotoxicity, achieving higher accuracy than single-fingerprint models.

bioRxiv · Jun 6, 2021Pharmacology & Toxicology