Z. Fang

This study compares the signalling, trafficking, and glucoregulatory effects of exendin-4 and lixisenatide, finding differences in cAMP signalling potency and receptor recycling that impact glucose control.

This study compares the gut microbiome of short-term and long-term medical workers to normal controls, finding significant structural changes linked to hospital exposure.

This study identifies SPIN1 as a regulator of the uL18-MDM2-p53 pathway, showing that SPIN1 promotes tumorigenesis by inhibiting p53 activation.

This study uses exome-capture RNA-sequencing on decade-old breast cancer specimens and matched bone metastases to identify clinically actionable gene expression changes in metastatic progression.