Author

A. Boon

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 6

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:host-pathogen & immune response· 5 Organism:mouse· 3 Assay:bulk RNA-seq· 1 Research Focus:ecology & biodiversity· 1 Organism:human· 1 Organism:non-human primate· 1 Assay:proteomics· 1

Frequent Co-Authors

D. Wang· 3 shared M. Diamond· 3 shared A. Joshi· 2 shared B. Whitener· 2 shared D. Fremont· 2 shared H. Zhao· 2 shared J. B. Case· 2 shared L. Adams· 2 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersMicrobiology

D. Wang

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6 papers

Recent·Most cited

Barcoded SARS-CoV-2 viruses define the impact of time and route of transmission on the transmission bottleneck in a Syrian hamster model.

R. F. Trende, T. L. Darling, T. Gan, D. Wang, A. Boon

This study uses barcoded SARS-CoV-2 viruses in Syrian hamsters to show that transmission bottleneck varies by exposure duration and route, with direct contact having the largest bottleneck.

bioRxiv · Jun 8, 2024 · PreprintMicrobiology

Prevalence of Bourbon and Heartland viruses in field collected ticks at an environmental field station in St. Louis County, Missouri, USA

I. D. Aziati, D. McFarland, A. Antia, A. Joshi, A. Aviles Gamboa, P. Lee, H. H. Harastani, D. Wang, S. A. Adalsteinsson, A. Boon

The study assesses the prevalence of Bourbon and Heartland viruses in ticks at an environmental field station, finding 3.9% and 7.6% positivity rates respectively.

bioRxiv · Mar 23, 2022Microbiology

Vaccine Protection Against the SARS-CoV-2 Omicron Variant in Macaques

A. Chandrashekar, J. Yu, K. McMahan, C. Jacob-Dolan, J. Liu, X. He, D. Hope, T. Anioke, J. Barrett, B. Chung, N. Hachmann, M. Lifton, J. Miller, O. Powers, M. Sciacca, , D. H. Barouch

This study evaluates vaccine efficacy against SARS-CoV-2 Omicron in macaques, finding that both humoral and cellular immune responses are necessary for virologic control.

bioRxiv · Feb 6, 2022Microbiology

mRNA-1273 and Ad26.COV2.S vaccines protect against the B.1.621 variant of SARS-CoV-2

T. L. Darling, B. Ying, B. Whitener, L. VanBlargan, T. L. Bricker, C.-Y. Liang, A. Joshi, G. Bamunuarachchi, K. Seehra, A. Schmitz, P. Halfmann, Y. Kawaoka, S. Elbashir, D. K. Edwards, L. Thackray, , A. Boon

This study evaluates the efficacy of mRNA-1273 and Ad26.COV2.S vaccines against the B.1.621 variant in mice and hamsters, showing protection against infection and pathology.

bioRxiv · Dec 29, 2021Microbiology

A potently neutralizing anti-SARS-CoV-2 antibody inhibits variants of concern by binding a highly conserved epitope

L. VanBlargan, L. Adams, Z. Liu, R. E. Chen, P. Gilchuk, S. Raju, B. Smith, H. Zhao, J. B. Case, E. S. Winkler, B. Whitener, L. Droit, I. Aziati, P.-Y. Shi, A. Creanga, , M. Diamond

The paper identifies an antibody that neutralizes all SARS-CoV-2 variants by targeting a conserved epitope on the spike protein.

bioRxiv · Apr 26, 2021Microbiology

A single intranasal or intramuscular immunization with chimpanzee adenovirus vectored SARS-CoV-2 vaccine protects against pneumonia in hamsters.

T. Bricker, T. Darling, A. Hassan, H. Harastani, A. Soung, X. Jiang, Y.-N. Dai, H. Zhao, L. Adams, M. Holtzman, A. Bailey, J. B. Case, D. Fremont, R. S. Klein, M. Diamond, A. Boon

This study compares intranasal and intramuscular delivery of a chimpanzee adenovirus-vectored SARS-CoV-2 vaccine in hamsters, finding that intranasal immunization provides superior protection against infection and inflammation.

bioRxiv · Dec 2, 2020Microbiology