Author

A. Fang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Organism:human· 3 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Assay:CRISPR screen· 1

Frequent Co-Authors

A. Phelps· 2 shared J. F. Koenig· 2 shared K. Bruton· 2 shared M. Jordana· 2 shared N. P. H. Knudsen· 2 shared P. S. Andersen· 2 shared S. Waserman· 2 shared A. Ariaz· 1 shared

Activity by Year

2022-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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2 shared papersImmunology

A. Phelps

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Efficient Genome Editing with Chimeric Oligonucleotide-Directed Editing

L. T. Nguyen, N. R. Rakestraw, B. L. M. Pizzano, C. B. Young, Y. Huang, K. T. Beerensson, A. Fang, S. G. Antal, K. V. Anamiss, C. M. D. Peggs, J. Yan, Y. Jing, R. D. Burdine, B. Adamson, J. E. Toettcher, , P. K. Jain

This paper introduces CODEMax and CODEMax(exo+) genome editing systems that enable efficient and precise search-and-replace editing in human cells with reduced off-target effects.

bioRxiv · Jul 9, 2024Bioengineering

Pathogenic IgE-fated memory B cell responses retain functional plasticity

K. Bruton, A. Phelps, A. Ariaz, A. Fang, T. Walker, J. Wen, S. S. Khavkine-Binstock, D. Della Libera, O. Mann-Delany, N. P. H. Knudsen, S. Gadkar, E. Grydziuszko, J. F. Koenig, A. Gagnon, S. Waserman, , M. Jordana

This study shows that blocking IL-4/IL-13 signaling can reprogram allergen-specific memory B cells from a pathogenic IgE fate to a non-pathogenic IgG2c fate.

bioRxiv · Nov 28, 2023Immunology

A Distinct Phenotype of Polarized Memory B cell holds IgE Memory

J. F. Koenig, N. P. H. Knudsen, A. Phelps, K. Bruton, I. Hoof, G. Lund, D. D. Libera, A. Lund, L. Christensen, D. R. Glass, T. D. Walker, A. Fang, S. Waserman, M. Jordana, P. S. Andersen

The paper identifies a novel memory B cell subset, MBC2s, that holds allergen-specific IgE memory and contributes to IgE production in allergic diseases.

bioRxiv · Jan 25, 2023 · PreprintImmunology

Porous microneedle patch with sustained exosome delivery repairs severe spinal cord injury

A. Fang, Y. Wang, N. Guan, L. Lin, B. Guo, W. Cai, X. Chen, J. Ye, Z. Abdelrahman, X. Li, Y. Zuo, H. Zheng, Z. Wu, S. Jin, K. Xu, , X. Wang

This study develops a microneedle patch that delivers mesenchymal stem cell-derived exosomes to treat spinal cord injury, showing improved tissue recovery and functional outcomes in rats.

bioRxiv · Jul 18, 2022 · PreprintBioengineering