Author

A. Sawant

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:development & morphogenesis· 1 Assay:flow cytometry· 1 Organism:human· 1

Frequent Co-Authors

C. Chan· 2 shared E. White· 2 shared F. Shi· 2 shared S. Ganesan· 2 shared A. Mukhopadhyay· 1 shared B. Schneider· 1 shared C. Hinrichs· 1 shared C. S. Hinrichs· 1 shared

Activity by Year

2023-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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2 shared papersCancer Biology

C. Chan

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Author profile →

3 papers

Recent·Most cited

Immune Checkpoint Blockade Delays Cancer and Extends Survival in Murine DNA Polymerase Mutator Syndromes

A. Sawant, F. Shi, E. C. Lopes, Z. Hu, S. Abdelfattah, J. Baul, J. Powers, C. Hinrichs, J. Rabinowitz, C. Chan, E. Lattime, S. Ganesan, E. White

This paper shows that immune checkpoint blockade (ICB) can delay cancer onset and improve survival in mice with mutator syndromes, but only if administered prophylactically before tumors develop.

bioRxiv · Jun 10, 2024 · PreprintCancer Biology

RESPIRATION DEFECTS LIMIT SERINE SYNTHESIS REQUIRED FOR LUNG CANCER GROWTH AND SURVIVAL

E. Cararo Lopes, F. Shi, A. Sawant, M. Ibrahim, M. Gomez-Jenkins, Z. S. Hu, P. Manchiraju, V. Bhatt, W. Wang, C. S. Hinrichs, D. C. Wallace, X. Su, J. D. Rabinowitz, C. Chan, J. Y. Guo, , E. White

This study shows that mitochondrial DNA mutations in NSCLC cause respiration defects, leading to glucose dependency, reduced serine synthesis, and increased cancer survival.

bioRxiv · May 28, 2024 · PreprintCancer Biology

A 30-Color Full-Spectrum Flow Cytometry Panel to Characterize the Immune Cell Landscape in Spleen and Tumors within a Syngeneic MC-38 Murine Colon Carcinoma Model

G. DeNiro, K. Que, S. M. Koo, J. Kim, B. Schneider, A. Mukhopadhyay, A. Sawant, T. A. Nguyen

bioRxiv · Feb 24, 2023Cancer Biology