Author

E. C. Lopes

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Assay:metabolomics· 1

Frequent Co-Authors

E. White· 2 shared A. Sawant· 1 shared C. Chan· 1 shared C. Hinrichs· 1 shared C. Li· 1 shared E. Lattime· 1 shared F. Shi· 1 shared J. Baul· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCancer Biology

E. White

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Immune Checkpoint Blockade Delays Cancer and Extends Survival in Murine DNA Polymerase Mutator Syndromes

A. Sawant, F. Shi, E. C. Lopes, Z. Hu, S. Abdelfattah, J. Baul, J. Powers, C. Hinrichs, J. Rabinowitz, C. Chan, E. Lattime, S. Ganesan, E. White

This paper shows that immune checkpoint blockade (ICB) can delay cancer onset and improve survival in mice with mutator syndromes, but only if administered prophylactically before tumors develop.

bioRxiv · Jun 10, 2024 · PreprintCancer Biology

G6PD Maintains Redox Homeostasis and Biosynthesis in LKB1-Deficient KRAS-Driven Lung Cancer

T. Lan, S. Arastu, S. Wang, J. Lam, W. Wang, V. Bhatt, E. C. Lopes, Z. S. Hu, M. Sun, X. Luo, J. M. Ghergurovich, C. Li, X. Su, J. D. Rabinowitz, E. White, J. Y. Guo

This study shows that G6PD is critical for redox balance and biosynthesis in LKB1-deficient KRAS-driven lung cancer, but not in KP tumors, and identifies potential therapeutic strategies.

bioRxiv · Oct 6, 2023 · PreprintCancer Biology