PI(3,5)P2 Controls the Signaling Activity of Class I PI3K
J. Sun, J. Zalejski, S. Song, A. Sharma, W. Wang, Y. Hu, W.-T. Lo, P. Koch, J. Singh, I. Singaram, B. An, J. Zhao, L.-W. Gong, V. Haucke, R. Gao, W. Cho
This study identifies PI(3,5)P2 as a regulator of Class I PI3K activity by interacting with its p85 subunit, revealing a feedback mechanism that impacts cancer and tissue repair.
bioRxiv · Jan 25, 2023 · PreprintBiochemistry