Author

B. Ding

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Plant Biology· 2 Cancer Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Organism:plant (other)· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:cryo-EM· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

A. Brown· 2 shared B. Chen· 2 shared K. Rottner· 2 shared L. E. Stanley· 2 shared M. Schaks· 2 shared S. Chowdhury· 2 shared S. Yang· 2 shared Y. Liu· 2 shared

Activity by Year

2018-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersBiochemistry

A. Brown

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Oncogenic Mutant p53 Sensitizes Non-Small Cell Lung Cancer Cells to Proteasome Inhibition via Oxidative Stress-Dependent Induction of Mitochondrial Apoptosis

K. K. Chougoni, V. Neely, B. Ding, E. Oduah, V. Lam, B. Hu, J. E. Koblinski, B. E. Windle, S. P. Deb, S. Deb, S. K. Radhakrishnan, H. Harada, S. R. Grossman

This study shows proteasome inhibitors are more effective against NSCLC cells with mutant p53 by inducing oxidative stress and mitochondrial apoptosis, suggesting a new therapeutic strategy.

bioRxiv · Feb 22, 2024Cancer Biology

Arf GTPase activates the WAVE Regulatory Complex through a novel binding site

S. Yang, Y. Liu, A. Brown, M. Schaks, B. Ding, D. A. Kramer, L. Ding, O. Alekhina, D. D. Billadeau, S. Chowdhury, J. Wang, K. Rottner, B. Chen

This study identifies a novel Arf1 binding site on WRC that drives activation through a mechanism distinct from Rac1.

bioRxiv · May 13, 2022 · PreprintBiochemistry

Structures reveal a key mechanism of WAVE Regulatory Complex activation by Rac1 GTPase

B. Ding, S. Yang, M. Schaks, Y. Liu, A. Brown, K. Rottner, S. Chowdhury, B. Chen

The paper reports WAVE Regulatory Complex structures bound to Rac1, revealing how Rac1 binding at the A site activates WRC to drive actin polymerization.

bioRxiv · May 10, 2022Biochemistry

The E3 Ubiquitin Ligase RNF5 Facilitates SARS-CoV-2 Membrane Protein-Mediated Virion Release

Z. Yuan, B. Ding

This study identifies RNF5 as an E3 ligase that ubiquitinates SARS-CoV-2 M protein at K15, stabilizing the M-E complex and inducing autophagy for viral release.

bioRxiv · Feb 28, 2021Microbiology

Formation of periodic pigment spots by the reaction-diffusion mechanism

B. Ding, E. L. Patterson, S. Holalu, J. Li, G. A. Johnson, L. E. Stanley, A. B. Greenlee, F. Peng, H. D. Bradshaw, B. K. Blackman, Y.-W. Yuan

The paper identifies an R2R3-MYB activator and an R3-MYB repressor in monkeyflowers that fit Turing's reaction-diffusion model and explain periodic pigment spot formation.

bioRxiv · Aug 30, 2018Plant Biology

Developmental genetics of corolla tube formation: role of the tasiRNA-ARF pathway

B. Ding, R. Xia, Q. Lin, V. Gurung, J. M. Sagawa, L. E. Stanley, M. Strobel, P. K. Diggle, B. C. Meyers, Y.-W. Yuan

This study identifies the tasiRNA-ARF pathway's role in corolla tube formation in Mimulus lewisii through mutant and transgenic analyses, showing its impact on auxin distribution and petal primordium growth.

bioRxiv · Jun 19, 2018Plant Biology