S. Deb

A powdery mildew core effector protein targets host endosome tethering complexes HOPS and CORVET

The paper identifies CSEP0214 as a core effector protein from Blumeria hordei that interacts with barley VPS18, disrupting endosomal tethering complexes and host immunity.

Xanthomonas oryzae pv. oryzae type-III effector TAL9b targets a broadly conserved disease susceptibility locus to promote pathogenesis in rice

This study identifies TAL9b as a Xoo effector targeting OsS5H/FNS-03g, a bifunctional protein whose product apigenin promotes bacterial blight in rice.

Oncogenic Mutant p53 Sensitizes Non-Small Cell Lung Cancer Cells to Proteasome Inhibition via Oxidative Stress-Dependent Induction of Mitochondrial Apoptosis

This study shows proteasome inhibitors are more effective against NSCLC cells with mutant p53 by inducing oxidative stress and mitochondrial apoptosis, suggesting a new therapeutic strategy.

Efficacy of dynamic eigenvalue in anticipating and distinguishing tipping points

This paper evaluates the effectiveness of dynamic eigenvalue as an early warning signal for detecting tipping points and transitions in dynamical systems, highlighting its strengths and limitations.

Early warning signals are hampered by a lack of critical transitions in empirical lake data

This study evaluates early warning signals for ecological regime shifts in lake data and finds few critical transitions, with mixed performance of prediction methods.

Tipping points in spatial ecosystems driven by correlated noise

This study examines how correlated noise affects tipping points in spatial ecosystems and evaluates early warning indicators for detecting these transitions.

Extraintestinal roles of intestinal vitamin D receptor in protecting against dysbiosis and tumorigenesis in breast cancer

This study shows that intestinal vitamin D receptor deficiency promotes breast cancer by causing gut dysbiosis, increased inflammation, and microbial translocation.

Powdery mildew effectors AVRA1 and BEC1016 target the ER J-domain protein HvERdj3B required for immunity in barley

Rising Temperature Drives Tipping Points in Mutualistic Networks

This study shows that rising temperatures can cause sudden collapse in mutualistic networks, with generalist species playing a key role in tipping points.

Pufferfish (Tetraodon cutcutia) sampled from freshwater river serves an intermediate reservoir of sucrose nonfermenting variant of Vibrio cholerae PS-4.

This study reports a sucrose nonfermenting Vibrio cholerae strain isolated from pufferfish skin, lacking the sucR gene and showing distinct genomic and phenotypic characteristics.

A bacterial derived plant- mimicking cytokinin hormone regulates social behaviour in a rice pathogen

This study identifies a bacterial cytokinin hormone produced by Xoo that regulates planktonic lifestyle and virulence in rice pathogens.

Phylogenomic analysis of the genus Pseudomonas and reclassification of P. humi, P. zeshuii, P. psychrotolerans, P. nitritireducens, P. pharmacofabricae and P. panacis are later heterotypic synonym of P. citronellolis Lang 2007, P. luteola, P. oryzihabitans, P. nitroreducens Lang 2007, P. fluvialis and P. marginalis (Brown 1918) Stevens 1925 (Approved Lists 1980), respectively

This paper reclassifies six Pseudomonas species as later heterotypic synonyms of other species based on phylogenomic and genomic analyses.

Rational nanotoolbox with theranostic potential for medicated pro-regenerative corneal implants

This paper develops a nano toolbox for corneal implants that enables drug release, infection response, regeneration promotion, and in situ monitoring of the corneal environment.