Author

C. Ruan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Assay:imaging· 1 Research Focus:metabolism & bioenergetics· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

A. Kroshilina· 1 shared C. Luo· 1 shared E. M. Bradshaw· 1 shared F. Yang· 1 shared G. Wang· 1 shared H. Zhu· 1 shared J. Lyu· 1 shared J. Zhou· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperImmunology

A. Kroshilina

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2 papers

Recent·Most cited

A peptide-centric local stability assay to unveil protein targets of diverse ligands

K. Li, S. Chen, K. Wang, Y. Wang, Z. Fang, J. Lyu, H. Zhu, Y. Li, T. Yu, F. Yang, X. Zhang, S. Guo, C. Ruan, J. Zhou, Q. Wang, , M. Ye

This paper introduces PELSA, a peptide-centric local stability assay that identifies ligand-binding regions across the proteome with high sensitivity and without ligand modification.

bioRxiv · Oct 17, 2023 · PreprintBiochemistry

A Novel Tmem119-tdTomato Reporter Mouse Model for Studying Microglia in the Central Nervous System

C. Ruan, L. Sun, A. Kroshilina, L. Beckers, P. L. De Jager, E. M. Bradshaw, S. Hasson, G. Wang, W. Elyaman

This paper introduces a Tmem119-tdTomato reporter mouse model to specifically study microglia in the CNS, showing tdTomato+ cells are microglia-specific and detectable in health and disease.

bioRxiv · Jun 10, 2019Immunology