Author

D. A. Mann

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Organism:mouse· 2 Organism:bacteria (other)· 1 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

F. Oakley· 2 shared J. Mann· 2 shared A. Collins· 1 shared A. Hedley· 1 shared A. J. McFarlane· 1 shared A. Santos-Ledo· 1 shared A. Stevenson· 1 shared A. Watson· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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2 shared papersCell Biology

F. Oakley

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

UCHL1-dependent control of Hypoxia-Inducible Factor Transcriptional Activity in Liver Disease.

A. Collins, R. Scott, C. L. Wilson, G. Abbate, G. B. Ecclestone, D. Biddles, F. Oakley, J. Mann, D. A. Mann, N. S. Kenneth

This study shows that UCHL1 regulates HIF1 activity in liver fibrosis by cleaving ubiquitin chains, increasing HIF1 levels, and promoting fibrosis.

bioRxiv · Jan 8, 2023 · PreprintCell Biology

Subtyping evaluation of Salmonella Enteritidis using SNP and core genome MLST with nanopore reads

Z. Xian, S. Li, D. A. Mann, Y. Huang, F. Xu, X. Wu, S. Tang, G. Zhang, A. Stevenson, C. Ge, X. Deng

This study evaluates the use of nanopore sequencing for SNP and cgMLST subtyping of Salmonella Enteritidis, showing high concordance with Illumina data despite sequencing errors.

bioRxiv · May 3, 2022 · PreprintMicrobiology

Maturation, developmental site, and pathology dictate murine neutrophil function

J. B. G. Mackey, A. J. McFarlane, T. Jamieson, R. Jackstadt, X. L. Raffo-Iraolagoitia, J. Secklehner, X. Cortes-Lavaud, F. Fercoq, W. Clarke, A. Hedley, K. Gilroy, S. Lilla, J. Vuononvirta, G. J. Graham, K. De Filippo, , L. M. Carlin

This study identifies Ly6G expression levels as a marker for neutrophil maturation stages and shows spleen-derived neutrophils mature faster with distinct transcriptional profiles.

bioRxiv · Jul 21, 2021 · PreprintImmunology

mTORC1-Plin3 pathway is essential to activate lipophagy and protects against hepatosteatosis.

M. Garcia-Macia, A. Santos-Ledo, J. Leslie, H. Paish, A. Watson, L. Borthwick, J. Mann, F. Oakley, V. I. Korolchuk, D. A. Mann

This study identifies the mTORC1-Plin3 pathway as essential for lipophagy, which protects against hepatosteatosis by promoting lipid droplet degradation.

bioRxiv · Oct 21, 2019Cell Biology