Author

D. DeNardo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Immunology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2 Organism:human· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

A. Crampton· 1 shared A. Gruszczynska· 1 shared A. Heard· 1 shared A. Kinne· 1 shared A. Ray· 1 shared A. V. Galkin· 1 shared B. L. Knolhoff· 1 shared C. Mpoy· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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1 shared paperCancer Biology

A. Crampton

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Dehydrated snakes reduce postprandial thermophily

J. L. Azzolini, T. B. Roderick, D. DeNardo

This study shows that dehydration reduces the postprandial thermophily in pythons, indicating a trade-off between body temperature regulation and water balance.

bioRxiv · Apr 5, 2023Physiology

Costimulatory domains direct distinct fates of CAR-driven T cell dysfunction

M. E. Selli, J. H. Landmann, M. Terekhova, J. Lattin, A. Heard, Y.-S. Hsu, T.-C. Chang, J. M. Warrington, H. Ha, N. Kingston, G. Hogg, M. Slade, M. M. Berrien-Elliot, M. Foster, S. Kersting-Schadek, , N. Singh

This study identifies that chronic activation of 41BB-based CARs leads to a novel T cell dysfunction state, distinct from exhaustion, which can be mitigated by disrupting FOXO3.

bioRxiv · Jan 26, 2023 · PreprintImmunology

Context-dependent triggering of STING-interferon signaling by CD11b agonists supports anti-tumor immunity in mouse models and human cancer patients

X. Liu, G. D. Hogg, c. zuo, J. M. Baer, V. E. Lander, L. Kang, N. C. Borcherding, B. L. Knolhoff, R. E. Osterhout, A. V. Galkin, J. M. Bruey, L. L. Carter, C. Mpoy, J. K. Schwarz, H. Park, , D. DeNardo

This study identifies how CD11b agonists trigger STING-interferon signaling in tumor-associated macrophages to enhance anti-tumor immunity in mouse models and human cancer patients.

bioRxiv · Mar 22, 2022 · PreprintCancer Biology

Stromal architecture directs early dissemination in pancreatic ductal adenocarcinoma

A. Ray, M. Callaway, N. Rodriguez-Merced, A. Crampton, M. Carlson, K. Emme, E. Ensminger, A. Kinne, J. Schrope, H. Rasmussen, H. Jiang, D. DeNardo, D. Wood, P. Provenzano

This study shows that stromal collagen structures in pancreatic ductal adenocarcinoma promote early dissemination from pre-malignant lesions and ongoing invasion, suggesting FAK inhibition or stroma normalization could limit metastasis.

bioRxiv · Feb 19, 2021Cancer Biology