Author

E. Cao

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Immunology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Assay:electrophysiology· 1 Organism:mouse· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Mortha· 1 shared A. Pinedo· 1 shared A. Zhang· 1 shared B. Forde· 1 shared C. Lin· 1 shared C. P. Lusk· 1 shared C. Streutker· 1 shared C. Wu· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperImmunology

A. Mortha

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Channel width modulates the permeability of DNA origami based nuclear pore mimics

Q. Feng, M. Saladin, C. Wu, E. Cao, W. Zheng, A. Zhang, P. Bhardwaj, X. Li, Q. Shen, L. E. Kapinos, M. Mariappan, C. P. Lusk, Y. Xiong, R. Y. H. Lim, C. Lin

The paper investigates how varying the width of DNA origami-based nuclear pore mimics affects permeability, showing that narrower pores restrict viral capsid passage while wider pores allow it with NTR assistance.

bioRxiv · May 9, 2024Biophysics

The cilia enriched oxysterol 7β,27-DHC is required for polycystin activation

K. Ha, N. Mundt, P. Bisignano, A. Pinedo, E. Cao, J. Reiter, D. Raleigh, M. Delling

This study identifies 7β,27-DHC as a critical oxysterol required for polycystin complex activation in cilia, revealing a lipid-mediated regulatory mechanism for ADPKD.

bioRxiv · Apr 13, 2022 · PreprintPhysiology

A gut commensal protozoa remotely shapes a lung niche for asthma-promoting eosinophils.

K. Burrows, L. Ngai, P. Chiaranunt, E. Cao, C. Streutker, B. Forde, L. O'Mahony, A. Mortha

This study shows that the gut protozoa Tritrichomonas musculis exacerbates asthma by promoting lung eosinophilia through a tripartite immune network.

bioRxiv · Mar 25, 2022 · PreprintImmunology

Inhibitory and Transport Mechanisms of the Human Cation-Chloride Cotransport KCC1

E. Cao, Y. Zhao, M. Zhou, J. Shen, Q. Wang

This study presents two cryo-EM structures of human KCC1, revealing its inward-open and outward-open states and the mechanism of inhibition by a small molecule.

bioRxiv · Jul 26, 2020 · PreprintBiophysics