E. Ho

Life stage impact on the human skin ecosystem: lipids and the microbial community

The paper investigates how life stages affect the human skin microbiome and lipid mediators, finding microbial correlations with lipid profiles and cytokine production.

Chemoproteomic Profiling Reveals that Anti-Cancer Natural Product Dankastatin B Covalently Targets Mitochondrial VDAC3

This study identifies dankastatin B as a covalent inhibitor of VDAC3 in breast cancer cells, revealing its mechanism of action through chemoproteomic profiling.

Age and micronutrient effects on the microbiome in a mouse model of zinc depletion and supplementation

This study examines how age and zinc diet affect the gut microbiome in mice, finding age has a stronger impact than zinc status on microbiome composition.

Electronic "photoreceptors" enable prosthetic vision with acuity matching the natural resolution in rats

This paper demonstrates a photovoltaic array design for high-acuity prosthetic vision in rats, achieving resolution matching natural visual limits with subretinal pixels.

Large-scale design and refinement of stable proteins using sequence-only models

The paper presents two neural network models for predicting and generating stable proteins based on amino acid sequences, showing improved stability in both expert-designed and model-generated proteins.

Vertical-junction Photodiodes for Smaller Pixels in Retinal Prostheses

The paper demonstrates vertical-junction photodiodes that maintain performance and stimulation efficiency at smaller pixel sizes for retinal prostheses.

Kinetics of Plasma cfDNA Predicts Clinical Response in Non-Small Cell Lung Cancer Patients

This study shows that changes in plasma cfDNA levels during chemotherapy predict clinical response in NSCLC patients, with specific insights for lung adenocarcinoma.

Interspecies comparative metagenomics reveals correlated gut microbiome functional capacities among vertebrates

This study compares gut metagenomes across 10 vertebrate species to identify conserved and variable microbial functional pathways, showing general similarity to human gut microbiomes but with notable differences in disease-related pathways.

An integrated gene catalog of the zebrafish gut microbiome reveals significant homology with mammalian microbiomes

The paper constructs a zebrafish gut microbiome gene catalog, showing significant homology with human and mouse microbiomes despite taxonomic differences.

Population genomics of the facultatively asexual duckweed Spirodela polyrhiza

The paper examines genetic diversity in the asexually reproducing duckweed Spirodela polyrhiza and finds low diversity with weak purifying selection, suggesting rare but not negligible sex at the population level.