Author

T. Ling

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 4 Cancer Biology· 2 Biophysics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Organism:human· 5 Assay:imaging· 5 Approach:statistical model· 4 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 2 Approach:deep learning· 2 Research Focus:drug response / drug discovery· 2

Frequent Co-Authors

D. Palanker· 4 shared B. Tan· 2 shared H. Chen· 2 shared H. Li· 2 shared L. Schmetterer· 2 shared R. Sabesan· 2 shared V. A. Barathi· 2 shared V. P. Pandiyan· 2 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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4 shared papersBioengineering

D. Palanker

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

WTAP, transcriptionally regulated by p65, promotes inflammation through m6A modification and phase separation

Y. Ge, R. Chen, T. Ling, B. Liu, J. Huang, Y. Cheng, Y. Lin, H. Chen, X. Xie, G. Xia, G. Luo, S. Yuan, A. Xu

This study identifies WTAP as a p65-regulated m6A writer that promotes inflammation via phase separation and m6A modification, offering a therapeutic target for hyperinflammation.

bioRxiv · Oct 30, 2023 · PreprintImmunology

Targeting Acute Myeloid Leukemia Stem Cells Through Perturbation of Mitochondrial Calcium

A. I. Sheth, K. Engel, H. Tolison, M. J. Althoff, M. L. Amaya, A. Krug, T. Young, S. Pei, S. B. Patel, M. Minhajuddin, A. Winters, R. Miller, I. Shelton, J. St-Germain, T. Ling, , C. T. Jordan

This study identifies mitochondrial calcium utilization as a metabolic requirement of venetoclax-resistant acute myeloid leukemia stem cells and shows that targeting mitochondrial calcium uptake can eradicate these cells.

bioRxiv · Oct 2, 2023Cancer Biology

Light-evoked deformations in rod photoreceptors, pigment epithelium and subretinal space revealed by prolonged and multilayered optoretinography

B. Tan, H. Li, Y. Zhuo, L. Han, R. Mupparapu, D. Nanni, V. A. Barathi, D. Palanker, L. Schmetterer, T. Ling

This paper introduces a new optoretinography technique that detects light-evoked deformations in multiple retinal structures, including rods, pigment epithelium, and subretinal space, with high sensitivity and spatial resolution.

bioRxiv · Mar 3, 2023Bioengineering

Phase-Restoring Subpixel Image Registration: Enhancing Motion Detection Performance in Fourier-domain Optical Coherence Tomography

H. Li, B. Tan, V. P. Pandiyan, V. A. Barathi, R. Sabesan, L. Schmetterer, T. Ling

This paper introduces PRESIR, a method to correct motion-related decorrelation noise in FD-OCT, improving motion detection sensitivity and accuracy.

bioRxiv · Jun 15, 2022Bioengineering

Interferometric imaging of thermal expansion for temperature control in retinal laser therapy

D. Veysset, T. Ling, Y. Zhuo, D. Palanker

The paper develops a method to precisely measure thermal properties and temperature changes in retinal tissue using laser heating and optical coherence tomography.

bioRxiv · Nov 23, 2021Bioengineering

Midkine noncanonically suppresses AMPK activation through disrupting the LKB1-STRAD-Mo25 complex

T. Xia, D. Chen, X. Liu, H. Qi, W. Wang, H. Chen, T. Ling, W. Otkur, C.-S. Zhang, J. Kim, S.-C. Lin, H.-l. Piao

This study shows that Midkine suppresses AMPK activation by disrupting the LKB1-STRAD-Mo25 complex, promoting cancer cell proliferation and correlating with poor clinical outcomes in specific cancers.

bioRxiv · Sep 27, 2021Cancer Biology

Vertical-junction Photodiodes for Smaller Pixels in Retinal Prostheses

T. W. Huang, T. I. Kamins, Z. C. Chen, B.-Y. Wang, M. B. Bhuckory, L. Galambos, E. Ho, T. Ling, S. Afshar, A. Shin, V. Zuckerman, J. S. Harris, K. Mathieson, D. Palanker

The paper demonstrates vertical-junction photodiodes that maintain performance and stimulation efficiency at smaller pixel sizes for retinal prostheses.

bioRxiv · Oct 28, 2020Bioengineering

On mechanisms of light-induced deformations in photoreceptors

K. C. Boyle, Z. C. Chen, T. Ling, V. P. Pandiyan, J. Kuchenbecker, R. Sabesan, D. Palanker

This study uses optical coherence tomography to measure light-induced deformations in photoreceptors and presents a model explaining the observed contraction and elongation.

bioRxiv · Jan 8, 2020Biophysics