Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
5 papers
Recent·Most cited
J. C. Caicedo, J. Arevalo, F. Piccioni, M.-A. Bray, C. L. Hartland, X. Wu, A. N. Brooks, A. Berger, J. S. Boehm, A. E. Carpenter, S. Singh
The paper uses Cell Painting to predict the functional impact of lung cancer variants by analyzing cell morphology at the single-cell level.
bioRxiv · Nov 18, 2021Cancer Biology
S. Lin, C. Larrue, B. K. A. Seong, N. V. Dharia, M. Kuljanin, C. Wechsler, G. Kugener, A. Robichaud, A. Conway, T. N. Mashaka, S. Mouche, B. Adane, J. Ryan, J. D. Mancias, S. T. Younger, , K. Stegmaier
This study identifies novel therapeutic targets for AML using an in vivo CRISPR screening platform, revealing SLC5A3 as a metabolic vulnerability and MARCH5 as an apoptosis regulator.
bioRxiv · Dec 28, 2020Cancer Biology
D. J. Merk, S. Hirsch, F. Tsiami, B. Walter, L. A. Haeusser, S. Babaei, J. Admar, N. Casadei, C. Roggia, M. Spohn, J. Schittenhelm, S. Singer, U. Schueller, F. Piccioni, N. S. Persky, , G. Tabatabai
This study identifies targetable genetic dependencies in ATRT using CRISPR and small-molecule screens, revealing CDK4/6 inhibitors as potent therapeutic options.
bioRxiv · Dec 9, 2020 · PreprintCancer Biology
D. P. Bondeson, B. R. Paolella, A. Asfaw, M. Rothberg, T. Skipper, C. Langan, A. Gonzalez, L. Surface, K. Ito, M. Kazachkova, W. N. Colgan, A. Warren, J. Dempster, J. M. Krill-Burger, M. Ericcson, , T. R. Golub
The paper identifies XPR1 and KIDINS220 as therapeutic targets in ovarian cancer by showing their role in phosphate dysregulation leading to cell death.
bioRxiv · Oct 16, 2020Cancer Biology
J. R. Prensner, O. M. Enache, V. Luria, K. Krug, K. R. Clauser, J. M. Dempster, A. Karger, L. Wang, K. Stumbraite, V. M. Wang, G. Botta, N. J. Lyons, A. Goodale, Z. Kalani, B. Fritchman, , T. R. Golub
The paper identifies non-canonical open reading frames (ORFs) that encode functional proteins essential for cancer cell survival, with one example, GREP1, showing preferential essentiality in breast cancer.
bioRxiv · Mar 10, 2020 · PreprintCancer Biology