Author

H. Rost

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cell Biology· 3 Immunology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Organism:C. elegans· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

O. Zaslaver· 3 shared A. Konvalinka· 2 shared C. M. McEvoy· 2 shared S. Clotet-Freixas· 2 shared A. B. Dart· 1 shared A. Boshart· 1 shared A. Finelli· 1 shared A. Hilfinger· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersCell Biology

O. Zaslaver

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Bacterial ADP-heptose initiates a revival stem cell program in the intestinal epithelium

S. Goyal, C. X. Guo, A. Ranger, D. K. Tsang, O. Singh, C. F. Harrigan, O. Zaslaver, H. Rost, H. Y. Gaisano, S. Yuzwa, N. Gao, J. L. Wrana, D. J. Philpott, S. D. Gray-Owen, S. Girardin

This study shows that bacterial ADP-heptose triggers a revival stem cell program in the intestinal epithelium by inducing Paneth cell dedifferentiation and ISC loss.

bioRxiv · Jan 15, 2024 · PreprintCell Biology

Single-cell profiling of healthy human kidney reveals features of sex-based transcriptional programs and tissue-specific immunity

C. M. McEvoy, J. M. Murphy, L. Zhang, S. Clotet-Freixas, J. A. Mathews, J. An, M. Karimzadeh, D. Pouyabahar, S. Su, O. Zaslaver, H. Rost, M. Arambewela, L. Y. Liu, S. Zhang, K. A. Lawson, , S. Q. Crome

This study profiles healthy human kidney cells from 19 donors to reveal sex-based transcriptional differences and tissue-specific immune features.

bioRxiv · Dec 9, 2021Immunology

Cell Sex and Sex Hormones Modulate Kidney Glucose and Glutamine Metabolism in Health and Diabetes

S. Clotet-Freixas, O. Zaslaver, C. Pastrello, M. Kotlyar, C. M. McEvoy, S. Farkona, A. Saha, A. Boshart, M. Chan, M. Riera, M. J. Soler, A. Isenbrandt, J. Lamontagne-Proulx, S. Pradeloux, K. Coulombe, , A. Konvalinka

This study shows that cell sex and sex hormones influence glucose and glutamine metabolism in kidney cells, with male cells showing increased metabolic stress and female cells showing better redox balance.

bioRxiv · Aug 23, 2021 · PreprintCell Biology

Cell size homeostasis is maintained by a circuitry involving a CDK4-determined target size that programs the cell size-dependent activation of p38

C. Tan, M. B. Ginzberg, R. Webster, S. Iyengar, J. Concannon, Y. Wang, D. S. Auld, J. L. Jenkins, H. Rost, A. Hilfinger, B. Derry, N. Patel, R. Kafri

The paper identifies CDK4 as a regulator of cell size target size, distinct from growth-promoting pathways, and proposes a model linking mTORC1, p38, and CDK4 in cell size homeostasis.

bioRxiv · Oct 14, 2020Cell Biology