Author

H.-B. Luo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:virus· 1

Frequent Co-Authors

X. Li· 2 shared Y.-Y. Huang· 2 shared Z. Li· 2 shared C.-G. Zhan· 1 shared D. Wu· 1 shared F. H. Yang· 1 shared G. Li· 1 shared H. Liu· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersBiophysics

X. Li

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Identify potent SARS-CoV-2 main protease inhibitors via accelerated free energy perturbation-based virtual screening of existing drugs

Z. Li, X. Li, Y.-Y. Huang, Y. Wu, L. Zhou, R. Liu, D. Wu, L. Zhang, H. Liu, X. Xu, Y. Zhang, J. Cui, C.-G. Zhan, X. Wang, H.-B. Luo

This paper identifies potent SARS-CoV-2 main protease inhibitors using accelerated free energy perturbation-based virtual screening of existing drugs, finding 15 inhibitors from 25 predicted drugs.

Proceedings of the National Academy of Sciences · Oct 13, 2020Peer-reviewedBiophysics

Enantiomers of Chloroquine and Hydroxychloroquine Exhibit Different Activities Against SARS-CoV-2 in vitro, Evidencing S-Hydroxychloroquine as a Potentially Superior Drug for COVID-19

G. Li, J. Sun, Y.-Y. Huang, Y. Li, Y. Shi, Z. Li, X. Li, F. H. Yang, J. Zhao, H.-B. LUO, T. Y. Zhang, X. Zhang

This study shows that S-enantiomers of chloroquine and hydroxychloroquine are more effective against SARS-CoV-2 and less toxic than their R-enantiomers, suggesting S-HCQ as a better treatment option for COVID-19.

bioRxiv · May 26, 2020 · PreprintBiochemistry