J. A. Richt

This study edits pigs to knock out TMPRSS2, reducing influenza A virus replication and shedding, with implications for controlling IAV in pigs.

This study identifies WDR7 as an essential host factor for Rift Valley fever phlebovirus and La Crosse encephalitis virus replication through CRISPR-Cas9 and siRNA screens.

This study shows Jamaican fruit bats are poorly susceptible to SARS-CoV-2 but develop a regulatory T cell-like immune response when transduced with human ACE2, leading to lung infection without overt disease.

This study compares the stability of SARS-CoV-2 ancestral and variant strains in human biological fluids, finding the ancestral strain more stable than Alpha, Beta, and Omicron in liquid samples.

This study examines reassortment dynamics of influenza A virus in guinea pigs, ferrets, and swine, finding reassortment is common but more frequent in ferrets and guinea pigs than swine, with spatial compartmentalization observed.

The paper shows SARS-CoV-2 Omicron variant infects white-tailed deer on Staten Island, with age-dependent antibody prevalence and evidence of human-to-deer spillover.

This study investigates sheep susceptibility to SARS-CoV-2 and finds that they show low susceptibility, with the alpha variant outcompeting the ancestral lineage.

This study evaluates how mutations in SARS-CoV-2 Spike protein affect viral entry and neutralization across animal ACE2 receptors and identifies key mutations that enhance viral entry and reduce antibody neutralization.

This study shows adult white-tailed deer are susceptible to SARS-CoV-2 and can transmit it vertically and horizontally, with the alpha variant outcompeting the ancestral strain.

This study shows SARS-CoV-2 variants of concern have mutations that increase spike cleavage and fusogenic capacity, enhancing viral transmission and cell entry.

This study examines the seasonal stability of SARS-CoV-2 in various human biological fluids, finding longer survival in winter and spring/fall conditions.

This study examines SARS-CoV-2 stability on surfaces under different environmental conditions, finding longer half-lives in spring/fall compared to indoor and summer conditions.

This study shows that SARS-CoV-2 can re-infect previously infected cats, but viral shedding is insufficient for transmission to naive cats.

This study develops and tests bat influenza-based live attenuated vaccines for pigs, showing they reduce viral replication and lesions without causing vaccine-associated enhanced respiratory disease.

This study investigates whether biting insects can transmit SARS-CoV-2 after ingesting an infected blood meal, finding no replication in tested species or cell lines.

This study assesses SARS-CoV-2 susceptibility in swine cells and pigs, finding replication in cell lines but no infection or transmission in pigs.

This study investigates SARS-CoV-2 infection, disease progression, and transmission in domestic cats through experimental challenge and monitoring.