Author

J. Crowdis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 5 Biochemistry· 1

Signature Assays, Organisms & Methods

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Organism:human· 5 Assay:whole-genome sequencing· 4 Research Focus:differential expression· 3 Approach:experimental assay· 3 Approach:statistical model· 3 Research Focus:cell type annotation· 2 Research Focus:clustering· 2 Research Focus:gene regulatory network inference· 2

Frequent Co-Authors

E. Van Allen· 4 shared A. K. Tewari· 3 shared M. Brown· 3 shared M. X. He· 3 shared S. H. AlDubayan· 3 shared S. Y. Camp· 3 shared A. T. M. Cheung· 2 shared J. Park· 2 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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4 shared papersCancer Biology

E. Van Allen

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Somatic structural variants driving distinct modes of oncogenesis in melanoma

J. M. Conway, R. Gillani, J. Crowdis, B. Reardon, J. Park, S. Han, B. Titchen, M. Benamar, R. Haq, E. Van Allen

This study analyzes structural variants in melanoma subtypes, identifying distinct genomic properties and molecular drivers that may inform therapeutic strategies.

bioRxiv · Nov 1, 2023 · PreprintCancer Biology

Analysis of evolutionary dynamics and clonal architecture in prostate cancer

J. Conway, A. K. Tewari, S. Y. Camp, S. Han, J. Crowdis, M. X. He, Y. A. Nyame, S. H. AlDubayan, N. Schultz, Z. Szallasi, M. M. Pomerantz, M. L. Freedman, L. Fong, P. S. Nelson, M. Brown, , E. Van Allen

This study analyzes prostate cancer clonal architecture and evolutionary dynamics in 845 tumors, finding that Black patients have more monoclonal tumors but higher recurrence rates, and identifies new mutational signatures linked to subclones.

bioRxiv · Mar 23, 2023 · PreprintCancer Biology

Glutathione supports lipid abundance in vivo

G. Asantewaa, E. T. Tuttle, N. P. Ward, Y. P. Kang, Y. Kim, M. E. Kavanagh, N. Girnius, Y. Chen, R. Duncan, K. Rodriguez, F. Hecht, M. Zocchi, L. Smorodintsev-Schiller, T. Q. Scales, K. Taylor, , I. S. Harris

This study shows that glutathione (GSH) is essential for lipid abundance in adult tissues, particularly in the liver, by repressing NRF2.

bioRxiv · Feb 10, 2023 · PreprintBiochemistry

A patient-driven clinicogenomic partnership through the Metastatic Prostate Cancer Project

J. Crowdis, S. Balch, L. Sterlin, B. S. Thomas, S. Y. Camp, M. Dunphy, E. Anastasio, S. Shah, A. L. Damon, R. Ramos, D. M. Sosa, I. K. Small, B. Tomson, C. M. Nguyen, M. McGillicuddy, , E. M. Van Allen

The paper describes a patient-driven initiative that collects clinicogenomic data from metastatic prostate cancer patients, revealing consistent patient-reported data and genomic insights from cfDNA samples.

bioRxiv · Jul 9, 2021 · PreprintCancer Biology

Molecular features of exceptional response to neoadjuvant anti-androgen therapy in high-risk localized prostate cancer

A. K. Tewari, A. T. M. Cheung, J. Crowdis, J. R. Conway, S. Y. Camp, S. A. Wankowicz, D. G. Livitz, J. Park, R. T. Lis, A. Boosma-Moody, M. X. He, S. H. AlDubayan, Z. Zhang, R. R. McKay, I. Leshchiner, , E. Van Allen

bioRxiv · Apr 20, 2021Cancer Biology

Subtype Heterogeneity and Epigenetic Convergence in Neuroendocrine Prostate Cancer

P. Cejas, Y. Xie, A. Font-Tello, K. Lim, S. Symala, X. Qiu, A. Tewari, N. Shah, H. Nguyen, R. Patel, L. Brown, I. Coleman, W. M. Hackeng, L. Brosens, K. Dreijerink, , H. W. Long

This study identifies two distinct subtypes of neuroendocrine prostate cancer based on neuronal transcription factors and highlights their epigenetic convergence and therapeutic implications.

bioRxiv · Sep 13, 2020Cancer Biology